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Sulpiride
go.drugbank.com/drugs/DB00391ApprovedWithdrawnSulpiride first appeared in published literature in 1967. … [A229683] Sulpiride is not approved by the FDA, Health Canada, or the EMA; though it is approved in individual European countries.[L24679]
Synonyms: N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide, 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamideCategories: MATE 1 Substrates, MATE 2 SubstratesEsmolol
go.drugbank.com/drugs/DB00187ApprovedInvestigationalWithdrawnThe FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride that supply 250 milligrams/milliliter of concentrated esmolol per 10-milliliter ampule … Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker.
Synonyms: Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate, (±)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamateCategories: Adrenergic beta-1 Receptor AntagonistsSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigational[A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243]
Mixtures: SEMİTONE 50/20 MG FILM TABLET, 10 ADET, SEMİTONE 100/20 MG FILM TABLET, 10 ADETProducts: SPYLACTON 100 MG FILM KAPLI TABLET, 20 ADET, SPYLACTON 50 MG FILM KAPLI TABLET, 20 ADETRemlarsen
go.drugbank.com/drugs/DB19131InvestigationalRemlarsen is under investigation in clinical trial NCT03601052 (Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids).
Synonyms: -cholest-5-en-3-yloxy)hexyl)oxy)-2-hydroxypropyl hydrogen phosphate), complex with rna ((2'-deoxy-2'-fluoro)u-a-g-(2'-deoxy-2'-fluoro)c-a-(2'-deoxy-2'-fluoro)c-(2'-de, Rna, (am-am-cm-a-cm-um-g-um-um-um-a-cm-a-a-a-um-g-g-um-cm-cm-um-a), 3'-(3-((6-((3.beta.)Bendamustine
go.drugbank.com/drugs/DB06769ApprovedInvestigationalThrough this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. … Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL).
Categories: Heterocyclic Compounds, 2-RingProducts: LEVACT 25 MG İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON , 10 ADET, LEVACT 25 MG İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON , 20 ADETHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigational[A180625] The efficacy of haloperidol was first established in controlled trials in the 1960s.[A180610] … However, these findings contradict the findings from studies in vitro with human liver microsomes and from drug interaction studies in vivo.
Synonyms: 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one, 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidineProducts: LEPTOL 20 MG TABLET , 20 ADET, NORODOL 20 MG TABLET, 20 ADETIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer. … [L50181, L50186, L50201] Irinotecan liposome was approved by the FDA in February 2024.[L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I.
Synonyms: (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl, )ethyl)piperidine-1-carboxylateCategories: Topoisomerase 1 (TOP1) inhibitorsAcetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedThis drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. … Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Synonyms: 2-Acetoxybenzoic acid, 2-Acetoxybenzenecarboxylic acidMixtures: Trinomia 100 mg/20 mg/10 mg Hartkapseln, THOMAPVRIN 250 mg/200 mg/50 mg TABLET, 10 ADETIdarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Synonyms: (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosideProducts: Idarubicin Accord 20 mg/20 ml Injektionslösung, İDAMEN IV 20 MG/20 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 FLAKONLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalIt was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). … interactions[L8606,L8600,L8615] - these characteristics make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in
Categories: Heterocyclic Compounds, 1-RingProducts: LEV-END 500 MG/5 ML KONSANTRE İNFÜZYON ÇÖZELTİSİ İÇEREN FLAKON, 10 ADET, LEV-END 250 MG FILM KAPLI TABLET, 50 ADET