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Gleptoferron
go.drugbank.com/drugs/DB11417ExperimentalVet approvedColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
Categories: Compounds used in a research, industrial, or household setting4-dimethylaminophenol
go.drugbank.com/drugs/DB13549ExperimentalCategories: Compounds used in a research, industrial, or household settingBOS172722
go.drugbank.com/drugs/DB15498InvestigationalThe key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects. … [A187120] An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone receptor negative breast cancer, and demonstrated promising synergistic effects.[A187123]
Tallimustine
go.drugbank.com/drugs/DB15466Experimental[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as [brostallicin], which have a favourable cytotoxicity … Tallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA.
Antilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalInduction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for its therapeutic effect in these conditions. … There are currently various ATG products available, which differ in the source of inoculated animal (rabbit, horse, or pig) and in the type of antigen product used to produce immunoglobulin (thymocytes
Synonyms: e-ATGApronalide
go.drugbank.com/drugs/DB13221ApprovedApronalide is approved in Japan. Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura [A174814].
D-glyceraldehyde 3-phosphate
go.drugbank.com/drugs/DB02263ExperimentalAn aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
NV-18
go.drugbank.com/drugs/DB05886ExperimentalLike phenoxodiol, NV-18 is broadly effective in the laboratory against almost all human cancer types, but NV-18 is distinctive in showing particular potency against melanoma and cholangiocarcinoma (cancer
PI-0824
go.drugbank.com/drugs/DB05516InvestigationalCurrently, most doctors who treat patients with PV will prescribe high-dose steroids and drugs that suppress the immune system in an effort to decrease the production of these antibodies. … Pemphigus vulgaris (PV) is an autoimmune disease affecting approximately 40,000 people worldwide.
Fontolizumab
go.drugbank.com/drugs/DB05111InvestigationalFontolizumab (marketed under the trade name HuZAF™) is a humanized monoclonal antibody which is used as an immunosuppressive drug to treat Crohn's disease.