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Prednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approvedPrednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
International brands: Ak-PredCategories: Corticosteroids, Weak (Group I), Corticosteroid Hormone Receptor AgonistsGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigationalIt also acts as an allosteric modulator of the nicotinic receptor, giving its dual mechanism of action clinical significance. … [L13571] It is therefore not considered to be a disease-modifying drug.
Products: GALANTAMIN ACTAVIS 8MG HK, REMINYL 1XTAEGL 8MG HK RETNicaraven
go.drugbank.com/drugs/DB06397ExperimentalCategories: Compounds used in a research, industrial, or household settingHuman interferon beta
go.drugbank.com/drugs/DB14999ApprovedInvestigationalHuman interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. … It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity.[A191733,L12012]
Categories: Interferon Type ITrilaciclib
go.drugbank.com/drugs/DB15442ApprovedInvestigational[L31828] CDK4 and CDK6 inhibitors have been investigated since the mid 1990s for their use in tumorigenesis and chemotherapy.[A229323] Trilaciclib was first described in the literature in 2016. … Trilaciclib, or G1T28, is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing
Categories: MATE 2-K InhibitorsMethoxamine
go.drugbank.com/drugs/DB00723ApprovedInvestigationalWithdrawnAn alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.
Categories: Adrenergic alpha-1 Receptor AgonistsEthyl biscoumacetate
go.drugbank.com/drugs/DB08794ApprovedWithdrawnEthyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
Categories: Vitamin K AntagonistsDG051
go.drugbank.com/drugs/DB05177ExperimentalDG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4 (LTB4), an end product of the leukotriene pathway and a potent promoter of inflammation. … DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack.
Piperacetazine
go.drugbank.com/drugs/DB06808ApprovedVet approvedWithdrawnPiperacetazine was an antipsychotic.
Miocamycin
go.drugbank.com/drugs/DB13287Approvedor as an alternative to erythromycin treatment [A176170]. … Miocamycin is a macrolide type antimicrobial [A176170]. This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia [L5737].