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Ramosetron
go.drugbank.com/drugs/DB09290InvestigationalIt is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron.
J147
go.drugbank.com/drugs/DB13957Experimental[A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging
AZD7442
go.drugbank.com/drugs/DB15787Investigational[L15596] It was developed by AstraZeneca with the goal of conferring at least 6 months of protection against COVID-19 - a significantly longer window of efficacy than that of other vaccines.[L15591]
OAV201
go.drugbank.com/drugs/DB17842ExperimentalIt was first developed by Novartis and investigated for the treatment of Rett syndrome, but further investigation in clinical trials was halted.[L46661]
Etryptamine
go.drugbank.com/drugs/DB01546ApprovedIllicitWithdrawnαET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine, a closely related compound.
Elagolix
go.drugbank.com/drugs/DB11979ApprovedInvestigationalIt has been determined that endometriosis is one of the most common gynecologic disorders in the United States [A35868, A35869, F801].
Pagoclone
go.drugbank.com/drugs/DB04903InvestigationalIt is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures
PSN9301
go.drugbank.com/drugs/DB05001ExperimentalPSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for meal-related dosing.
SC12267
go.drugbank.com/drugs/DB05125InvestigationalThrough highly selective inhibition of pyrimidine biosynthesis, it controls the growth of rapidly proliferating cells, especially of lymphocytes, which are important for the immune response.
Gevokizumab
go.drugbank.com/drugs/DB12119InvestigationalIt has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors.