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Displaying results 4321 - 4330 of 10000 in total
  1. Drug

    MGC030

    go.drugbank.com/drugs/DB33973
    Experimental

    MGC030 is a biologic drug. MGC030 is under investigation in clinical trial NCT07822399 (A Study of MGC030 in Participants With Advanced Solid Tumors).

  2. Drug

    VH5356136

    go.drugbank.com/drugs/DB33975
    Experimental

    VH5356136 is a small molecule drug. … VH5356136 is under investigation in clinical trial NCT07822477 (A Study to Investigate Safety, Tolerability and Pharmacokinetics of VH5356136 in Adult Participants Without HIV).

  3. Drug

    MWN117

    go.drugbank.com/drugs/DB33969
    Experimental

    MWN117 is a small molecule drug. MWN117 is under investigation in clinical trial NCT07824804 (Phase 1 Clinical Study of MWN117 Injection in Healthy Participants and Participants With Obesity).

  4. Drug

    CM583

    go.drugbank.com/drugs/DB33976
    Experimental

    CM583 is a small molecule drug. CM583 is under investigation in clinical trial NCT07823764 (Study of CM583 in Healthy Participants).

  5. Drug

    Patisiran

    go.drugbank.com/drugs/DB14582
    Approved

    It is marketed as Onpattro which is formulated as patisiran within a liposome envelope for better delivery to the liver, where transthyretin is produced. … Patisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy caused by hereditary transthyretin-mediated amyloidosis [L4220].

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Floxuridine

    go.drugbank.com/drugs/DB00322
    ApprovedInvestigational

    An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. … When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate.

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil, 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil
  7. Drug

    Nitroprusside

    go.drugbank.com/drugs/DB00325
    ApprovedInvestigational

    Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). … Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.

    Categories: Compounds used in a research, industrial, or household settingProducts: N-PRUS, PRUSIAT®
  8. Drug

    Calcium glucoheptonate

    go.drugbank.com/drugs/DB00326
    ApprovedInvestigational

    Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. … Calcium is also needed for the heart, muscles, and nervous system to work properly.

    Synonyms: Calcium glucoheptonate (1:2), calcium bis[(2ξ)-D-glycero-D-gulo-heptonate]
  9. Drug

    Trimethadione

    go.drugbank.com/drugs/DB00347
    ApprovedWithdrawn

    An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  10. Drug

    Nitisinone

    go.drugbank.com/drugs/DB00348
    Approved

    Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1 and Alkaptonuria. … It is sold under the brand names Orfadin and Harliku. [L53253, L53258]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedione