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Displaying results 4321 - 4330 of 8520 in total
  1. Drug

    CERE-120

    go.drugbank.com/drugs/DB05637
    Investigational

    It was under investigation in clinical trials for the treatment of Parkinson's Disease. … CERE-120 is an investigational drug consisting of an adeno-associated virus (AAV) that was engineered to carry the human gene for neurturin, a neurotrophic (growth) factor.

  2. Drug

    Galsulfase

    go.drugbank.com/drugs/DB01279
    ApprovedInvestigational

    The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular

  3. Drug

    Dolcanatide

    go.drugbank.com/drugs/DB13112
    Investigational

    Dolcanatide has been investigated in Exposure.

  4. Drug

    LC16M8

    go.drugbank.com/drugs/DB05019
    Investigational

    LC16m8 is a next-generation, attenuated smallpox vaccine that is designed to have a better safety profile, yet be equally effective, compared to conventional smallpox vaccines. It is the only attenuated vaccine to be licensed for use in ...

  5. Drug

    Imlifidase

    go.drugbank.com/drugs/DB15258
    ApprovedInvestigational

    [L28001] As a result, the risk of antibody-mediated rejection is reduced allowing kidney transplantation in highly sensitized patients to proceed.[A225836,L28001] … [A225836] As a result, highly sensitized individuals experience marked delays on transplant lists due to the challenges associated with procuring an HLA compatible donor graft.

  6. Drug

    Vevorisertib

    go.drugbank.com/drugs/DB21481
    Investigational

    Vevorisertib has a monoisotopic molecular weight of 586.32 Da. … Vevorisertib is under investigation in clinical trial NCT02761694 (Vevorisertib (ARQ 751) as a Single Agent or in Combination With Other Anti-Cancer Agents, in Solid Tumors With PIK3CA / AKT / PTEN Mutations

  7. Drug

    BMS-986104

    go.drugbank.com/drugs/DB15214
    Investigational

    of BMS-986104 in Healthy Male Subjects). … BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

  8. Drug

    Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells

    go.drugbank.com/drugs/DB15731
    Investigational

    Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified on MSCs with enhanced clonogenicity and immunomodulatory properties.

  9. Drug

    Adomeglivant

    go.drugbank.com/drugs/DB11704
    Investigational

    Adomeglivant has been investigated for the basic science of Type 2 Diabetes.

  10. Drug

    Placulumab

    go.drugbank.com/drugs/DB11983
    Investigational

    Placulumab has been used in trials studying the treatment of Rheumatoid Arthritis.