Imlifidase

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Imlifidase
Accession Number
DB15258
Description

Imlifidase is under investigation in clinical trial NCT02854059 (IdeS in Asymptomatic Asymptomatic Antibody-Mediated Thrombotic Thrombocytopenic Purpura (TTP) Patients).

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Protein Based Therapies
Recombinant Enzymes
Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
  • HMED-IdeS
  • IdeS
  • IdeS recombinant
  • Imlifidase

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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International/Other Brands
Idefirix

Categories

ATC Codes
L04AA41 — Imlifidase
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Chemical Identifiers

UNII
UVJ7NL8S2P
CAS number
1947415-68-0

References

General References
Not Available
KEGG Drug
D11470
Wikipedia
Imlifidase

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4RecruitingTreatmentHepatitis B Chronic Infection1
4Unknown StatusTreatmentViral Hepatitis B1
2CompletedTreatmentAnti-Glomerular Basement Membrane Disease1
2CompletedTreatmentChronic Kidney Disease (CKD)1
2CompletedTreatmentChronic Renal Failure (CRF)1
2CompletedTreatmentEnd Stage Kidney Disease1
2RecruitingTreatmentGuillain-Barré Syndrome (GBS)1
2RecruitingTreatmentKidney Transplant Rejection1
2TerminatedTreatmentThrombotic Thrombocytopenic Purpura (TTP)1
1CompletedTreatmentHealthy Volunteers1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on May 20, 2019 09:05 / Updated on September 24, 2020 05:24

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