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Displaying results 4341 - 4350 of 10000 in total
  1. Drug

    Rabusertib

    go.drugbank.com/drugs/DB11662
    Investigational

    Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Daprodustat

    go.drugbank.com/drugs/DB11682
    ApprovedInvestigational

    [A254157] A phase 3 clinical trial (NCT02879305) found that in patients with CKD undergoing dialysis, daprodustat was non-inferior to erythropoiesis-stimulating agents regarding the change in the hemoglobin … Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.

    Synonyms: Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)-Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  3. Drug

    Iferanserin

    go.drugbank.com/drugs/DB11686
    Investigational

    Iferanserin has been investigated for the treatment of Hemorrhoids.

    Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor Antagonists
  4. Drug

    2-chloroethyl-3-sarcosinamide-1-nitrosourea

    go.drugbank.com/drugs/DB11688
    Investigational

    2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific

    Synonyms: 2-chloroethyl-3-sarcosinamide-1-nitrosourea, ACETAMIDE, 2-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)METHYLAMINO)-
  5. Drug

    Ilorasertib

    go.drugbank.com/drugs/DB11694
    Investigational

    Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.

    Synonyms: 1-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea, 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl)urea)Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Ipragliflozin

    go.drugbank.com/drugs/DB11698
    Investigational

    Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.

    Categories: Heterocyclic Compounds, 1-Ring, Sodium-Glucose Transporter 2 Inhibitors
  7. Drug

    Adomeglivant

    go.drugbank.com/drugs/DB11704
    Investigational

    Adomeglivant has been investigated for the basic science of Type 2 Diabetes.

  8. Drug

    Peficitinib

    go.drugbank.com/drugs/DB11708
    Investigational

    Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Dutogliptin

    go.drugbank.com/drugs/DB11723
    Investigational

    Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.

  10. Drug

    Ipatasertib

    go.drugbank.com/drugs/DB11743
    Investigational

    Ipatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.

    Categories: Heterocyclic Compounds, 1-Ring, Proto-Oncogene Proteins c-akt, antagonists & inhibitors