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Displaying results 4341 - 4350 of 10000 in total
  1. Drug

    Sinefungin

    go.drugbank.com/drugs/DB01910
    Experimental

    Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar.

    Synonyms: (2S,5S)-2,5-diamino-6-[(2R,3S,R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]hexanoic acid, 6,9-Diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-beta-D-ribo-decofuranuronic acidCategories: Heterocyclic Compounds, 2-Ring
  2. Indication

    Primary keratoconjunctivitis caused by herpes simplex virus type 2

    go.drugbank.com/conditions/DBCOND0021195
    Drugs: Trifluridine
    Synonyms: Primary keratoconjunctivitis caused by herpes simplex virus type 2
  3. Drug

    Iopromide

    go.drugbank.com/drugs/DB09156
    Approved

    favorable safety profile, with only 0.7% of patients in a 2 years study experiencing adverse events. … Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration.

    Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedSynonyms: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamide
  4. Drug

    Vardenafil

    go.drugbank.com/drugs/DB00862
    Approved

    Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction. … [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension has also been evaluated.[A258308]

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: VAREKSİL 20 MG FİLM KAPLI TABLET, 2 ADET, Varoni 20 mg Film Kaplı Tablet, 2 ADET
  5. Drug

    Baloxavir marboxil

    go.drugbank.com/drugs/DB13997
    ApprovedInvestigational

    [A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure. … [L4779] It was also approved by the European Commission on January 7, 2021.[L45241]

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADET, XOFLUZA 40 MG FİLM KAPLI TABLET, 2 ADET
  6. Drug

    Ibandronate

    go.drugbank.com/drugs/DB00710
    ApprovedInvestigational

    Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid]. … [L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.[A203138] Ibandronate was granted FDA approval on 16 May 2003.[L13805]

    Mixtures: IBAMIN D3 150 MG/2800 IU FİLM KAPLI TABLET, 3 ADET, İBAMIN D3 150 MG/2800 IU GRANÜL İÇEREN SAŞE ,3 SAŞEProducts: BONDRONAT 2 MG/2 ML AMPUL, 5 ADET, Ibandronsäure Sandoz 2 mg - Konzentrat zur Herstellung einer Infusionslösung
  7. Drug

    fb-PMT

    go.drugbank.com/drugs/DB17394
    Investigational

    Synonyms: 2-(4-(4-((1-(107- (4-(fluorophenyl)methoxy)-polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5- diiodophenoxy)-3,5-diiodophenyl)acetic acid, O,O'-Bis({4-[3,5-diiodo-4-(1-methylene-1,2,3-triazol-4-ylmethoxy)phenoxy]-3,5-diiodophenyl}acetic acid)polyethylene glycol
  8. Drug

    p-Coumaric acid

    go.drugbank.com/drugs/DB04066
    Experimental

    Categories: Compounds used in a research, industrial, or household settingSynonyms: (E)-3-(4-hydroxyphenyl)-2-propenoic acid, (2E)-3-(4-hydroxyphenyl)acrylic acid
  9. Drug

    Evolocumab

    go.drugbank.com/drugs/DB09303
    ApprovedInvestigational

    Evolocumab is a human IgG2 monoclonal antibody that targets the proprotein convertase subtilisin/kexin type 9 (PCSK9). … PCSK9 is a protein that targets LDL receptors for degradation, therefore reducing the liver's ability to remove LDL-cholesterol (LDL-C), or "bad" cholesterol, from the blood.

    Products: REPATHA 140 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR KALEM, 2 ADET, REPATHA® 140 MG/ML
  10. Drug

    Fosfomycin

    go.drugbank.com/drugs/DB00828
    ApprovedInvestigational

    [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile, fosfomycin has largely become a first-line therapeutic option for the treatment of uncomplicated … [A230348] In terms of chemical structure, fosfomycin is a phosphoenolpyruvate analog and contains a phosphonic group and an epoxide ring.

    Synonyms: (2R-cis)-(3-Methyloxiranyl)phosphonic acid, (1R,2S)-epoxypropylphosphonic acidProducts: SOLUFOS® 500 MG, ACECNOU® 2 G