Sinefungin

DB01910ExperimentalSmall molecule

Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include... The proteins that adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and modification methylase RsrI.

Chemical structure of Sinefungin
Formula / weight
C15H23N7O5 · 381.387 g/mol (avg)
Also known as
Adenosyl-ornithine
Code names
A 9145 · Antibiotic A 9145 · LILLY 57926 · LY-57926

Resolves to

Compound
UNIIW2U467CIILCAS58944-73-3ChEMBLCHEMBL1214186ChEBI45453PubChem65482KEGGD05846
Structure
InChIKeyLMXOHSDXUQEUSF-YECHIGJVSA-NSMILES[H][C@](N)(CC[C@]([H])(N)C(O)=O)C[C@@]1([H])O[C@@]([H])(N2C=NC3=C(N)N=CN=C23)[C@]([H])(O)[C@]1([H])O
Targets
P14751rsrIMQ54527rdmBP13956ermC'P14385taqIM

What you can answer from here — as of September 12, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
14Drug interactionsStructured to mechanism, not free text
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Sinefungin, and which of those have an active Phase 3 trial?

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