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Talimogene laherparepvec
go.drugbank.com/drugs/DB13896ApprovedInvestigationalIt is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities.
Synonyms: T Vec, T-VecEquine Botulinum Neurotoxin E Immune FAB2
go.drugbank.com/drugs/DB13897ApprovedEquine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype E. … It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes E in adults and pediatric patients.
Synonyms: Botulinum Neurotoxin E immune FAB2 (equine), BOTULINUM NEUROTOXIN E IMMUNE FAB2, EQUINEEquine Botulinum Neurotoxin C Immune FAB2
go.drugbank.com/drugs/DB13898ApprovedEquine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype C. … It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes C in adults and pediatric patients.
Synonyms: Botulinum Neurotoxin C immune FAB2 (equine), BOTULINUM NEUROTOXIN C IMMUNE FAB2, EQUINEEquine Botulinum Neurotoxin B Immune FAB2
go.drugbank.com/drugs/DB13903ApprovedEquine Botulinum Neurotoxin B Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype B. … It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes B in adults and pediatric patients.
Synonyms: Botulinum Neurotoxin B immune FAB2 (equine), BOTULINUM NEUROTOXIN B IMMUNE FAB2, EQUINECat dander extract
go.drugbank.com/drugs/DB13904ApprovedIt is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats.
2'-C-methylcytidine
go.drugbank.com/drugs/DB13921ExperimentalA nucleoside analog with anti-hepatitis C virus (HCV) activity. … Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'C-Me-C, 2'-C-MecytosinEmrusolmin
go.drugbank.com/drugs/DB13927InvestigationalEmrusolmin restores hippocampal synaptic and transcriptional plasticity as well as spatial memory in a mouse model for Alzheimer's disease, when given orally before or after the onset of pathology.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 1H-PYRAZOLE, 3-(1,3-BENZODIOXOL-5-YL)-5-(3-BROMOPHENYL)-, 3-(1,3-BENZODIOXOL-5-YL)-5-(3-BROMOPHENYL)-1H-PYRAZOLEUlixertinib
go.drugbank.com/drugs/DB13930InvestigationalUlixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity [A31474]. … It is currently in clinical trials for the treatment of a wide range of tumors.
Categories: Heterocyclic Compounds, 1-RingVoretigene neparvovec
go.drugbank.com/drugs/DB13932ApprovedInvestigational[L1094] An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. … [A31477] An advantage of this adeno-associated virus is the high predictability, unlike retrovirus, as they associate with a specific region of the human cellular genome localized in the chromosome 19.
Vosilasarm
go.drugbank.com/drugs/DB13939InvestigationalRAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.
Synonyms: 2-Chloro-4-(((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropyl)amino)-3-methylbenzonitrileCategories: Heterocyclic Compounds, 1-Ring