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Displaying results 4371 - 4380 of 10000 in total
  1. Drug

    Carbocromen

    go.drugbank.com/drugs/DB13279
    ApprovedWithdrawn

    Carbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development [L5635].

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    Methylthioninium

    go.drugbank.com/drugs/DB08167
    Investigational

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  3. Drug

    Alectinib

    go.drugbank.com/drugs/DB11363
    ApprovedInvestigational

    It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC … Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase.

    Synonyms: 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitors
  4. Drug

    Metrizoic acid

    go.drugbank.com/drugs/DB09346
    Approved

    Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. … A total of 10, 000 injections were administered to 2,028 patients undergoing angiocardiographic procedures over a three-year period.

    Categories: X-Ray Contrast Activity, X-Ray Contrast Media, Iodinated
  5. Drug

    (5Z,7E,9)-decatrien-2-one

    go.drugbank.com/drugs/DB15619
    Investigational

    An compound produced by _Fomitopsis betulina_, an edible fungus commonly called the birch polypore. Similar to [(5E,7E,9)-decatrien-2-one], it has a strong pineapple aroma.[A191116]

    Synonyms: (5Z,7E,9)-decatrien-2-one
  6. Drug

    Amifostine

    go.drugbank.com/drugs/DB01143
    ApprovedInvestigational

    A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

    Categories: Compounds used in a research, industrial, or household settingProducts: ETHYOL 500 MG IV INFUZYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET
  7. Drug

    Doxofylline

    go.drugbank.com/drugs/DB09273
    Investigational

    Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. … Decreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline [L1169].

    Mixtures: MUCOFIX 600/200 MG EFERVESAN, 5 ADET, MUCOFIX 1200/400 MG EFERVESAN TABLET, 5 ADETCategories: Cytochrome P-450 Substrates, Adrenergic beta-2 Receptor Agonists
  8. Drug

    Metiamide

    go.drugbank.com/drugs/DB08805
    Experimental

    Metiamide is an H-2 receptor antagonist derived from burimamide. It was an intermediate product on the path to developing cimetidine.

  9. Drug

    Primidone

    go.drugbank.com/drugs/DB00794
    ApprovedVet approved

    Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. … [L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112]

    Synonyms: 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dione, 2-deoxyphenobarbitalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inducers
  10. Drug

    Cloxazolam

    go.drugbank.com/drugs/DB01553
    Experimental

    The usual dose of cloxazolam in adults is 3-12mg/day for anti-anxiety. … As well, it has also been studied in Japan in doses of 15-30mg/day as an adjunct in the treatment of intractable epilepsy, for which it has demonstrated effectiveness.

    Categories: Heterocyclic Compounds, 2-RingProducts: OLCADIL ® 2 MG COMPRIMIDOS, OLCADIL ® 1 MG COMPRIMIDOS