Methylthioninium

DB08167InvestigationalSmall moleculeOxidation-Reduction Agent

Methylthioninium is the phenothiazine cation in methylene blue commonly used to treat methemoglobinemia. A medication used to treat a specific blood disorder related to poisoning.

Mechanism: Pharmacologically active on Acetylcholinesterase
Curator reviewed
Formula / weight: C₁₆H₁₈N₃S · 284.399 g/mol (avg)

Resolves to

Compound

UNIIZMZ79891ZHCAS7060-82-4ChEMBLCHEMBL191083ChEBI43830PubChem4139

Clinical / RWD

RxNorm1546414

Structure

InChIKeyRBTBFTRPCNLSDE-UHFFFAOYSA-NSMILESCN(C)C1=CC2=[S+]C3=CC(=CC=C3N=C2C=C1)N(C)C

Targets

P22303ACHEQ8NMG3Transcriptional regulator

What you can answer from here — as of April 02, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

241Drug interactionsStructured to mechanism, not free text

4Clinical trialsPhase, status and sponsor resolved per trial

1Structured indicationCondition, population, route and combination as fields, not prose

5ContraindicationsEach with its own population and attribute set

9Marketed productsAcross 1 country and 3 labellers

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Methylthioninium, and which of those have an active Phase 3 trial?

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