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Displaying results 4371 - 4380 of 9322 in total
  1. Drug

    Potassium guaiacolsulfonate

    go.drugbank.com/drugs/DB13735
    ApprovedWithdrawn

    Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest congestion.

  2. Drug

    Gantenerumab

    go.drugbank.com/drugs/DB12034
    Investigational

    to reduce Aβ aggregation and remove Aβ plaques. … Gantenerumab binds to a unique Aβ epitope compared to other anti-Aβ antibodies and preferentially recognizes Aβ oligomers and fibrils over monomers.[A244720]

  3. Drug

    Brivaracetam

    go.drugbank.com/drugs/DB05541
    ApprovedInvestigational

    It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 [L760]. … Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184].

  4. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell. … AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells.

    Synonyms: Nucleic acid aptamer binding to tumor cell nucleon
  5. Drug

    Arachidonic Acid

    go.drugbank.com/drugs/DB04557
    ApprovedInvestigationalWithdrawn

    It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. [PubChem] … It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides.

  6. Drug

    COVID19 s-vax loaded autologous dendritic cell vaccine

    go.drugbank.com/drugs/DB15814
    Experimental

    As of May 2020, the company is pursuing a human clinical trial (ChiCTR2000033003) to test the safety and immunogenicity of the vaccine. … , and are able to present antigens through costimulatory signals required for activation of CD4+ and CD8+ T-cells.

  7. Drug

    CG7870

    go.drugbank.com/drugs/DB04981
    Investigational

    It is a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.

  8. Drug

    Metocurine

    go.drugbank.com/drugs/DB01336
    Approved

    Patients on chronic anticonvulsant drugs are relatively resistant to metocurine. [A2393]

  9. Drug

    Aniline

    go.drugbank.com/drugs/DB06728
    Investigational

    Being a precursor to many industrial chemicals, its main use is in the manufacture of precursors to polyurethane. Like most volatile amines, it possesses the somewhat unpleasant odour of rotten fish. … Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine.

  10. Drug

    L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal

    go.drugbank.com/drugs/DB06124
    Experimental

    C-101, also called Myodur, is developed for the treatment of Duchenne’s muscular dystrophy (DMD) which is a morbid genetic disease that can lead to death in late adolescence due to accelerated skeletal … Calpain is the primary protease that degrades skeletal muscle.