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Displaying results 4381 - 4390 of 10000 in total
  1. Drug

    Baricitinib

    go.drugbank.com/drugs/DB11817
    ApprovedInvestigational

    Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. … [A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with [remdesivir] under the Emergency Use Authorization (EUA) in November 2020,[L22619] the FDA fully approved

    Categories: MATE 2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: UNAMÄ°TY 4 MG FÄ°LM KAPLI TABLET, 7 ADET, UNAMÄ°TY 2 MG FÄ°LM KAPLI TABLET, 7 ADET
  2. Drug

    Retosiban

    go.drugbank.com/drugs/DB11818
    Investigational

    Retosiban has been used in trials studying the treatment of Premature Labor and Obstetric Labour, Premature.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    ASP-4058

    go.drugbank.com/drugs/DB11819
    Investigational

    ASP4058 has been used in trials studying Food Effect of ASP4058 and Pharmacokinetics of ASP4058.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  4. Drug

    Danegaptide

    go.drugbank.com/drugs/DB11821
    Investigational

    Danegaptide has been investigated for the treatment of Focus of Study is STEMI.

  5. Drug

    Pritelivir

    go.drugbank.com/drugs/DB11844
    Investigational

    Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  6. Drug

    Revefenacin

    go.drugbank.com/drugs/DB11855
    ApprovedInvestigational

    The LAMA group falls into a parent category known as long-acting inhaled bronchodilators and this type of agents are recommended as a maintenance therapy for chronic obstructive pulmonary disease (COPD … [A40026] It was developed by Theravance Biopharma and FDA approved on November 9, 2018.[L4818]

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  7. Drug

    Ligelizumab

    go.drugbank.com/drugs/DB11856
    Investigational

    Ligelizumab is a humanized IgG1k monoclonal antibody targeted against immunoglobulin E (IgE). … Similar in mechanism to [omalizumab], another IgE-directed monoclonal antibody, ligelizumab has a distinct binding epitope as compared to its peer (with a small degree of overlap) which appears to confer

  8. Drug

    Litronesib

    go.drugbank.com/drugs/DB11861
    Investigational

    Litronesib has been used in trials studying the treatment of Solid Tumors, Ovarian Cancer, Gastric Cancer, Prostate Cancer, and Acute Leukaemia, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Preladenant

    go.drugbank.com/drugs/DB11864
    Investigational

    Preladenant has been used in trials studying the treatment of Brain Diseases, Parkinson Disease, Movement Disorders, Antipsychotic Agents, and Parkinsonian Disorders, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Brivanib alaninate

    go.drugbank.com/drugs/DB11865
    Investigational

    Brivanib alaninate has been investigated for the treatment of Colorectal Cancer.

    Categories: Heterocyclic Compounds, 1-Ring