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Displaying results 4381 - 4390 of 10000 in total

Drug
NS-2359
go.drugbank.com/drugs/DB05805
Investigational
This mode of action is expected to produce an optimal reduction in all disease symptoms and the possibility of an earlier onset of action compared to antidepressants already on the market. … NS2359 is a triple monoamine re-uptake inhibitor with a new, unique drug profile expected to yield important benefits compared to existing treatments of depression.
Drug
Paliroden
go.drugbank.com/drugs/DB05454
Investigational
Paliroden is an orally active neurotrophic, non-peptidic compound that activates synthesis of endogenous neurotrophines. … It is indicated for use in Alzheimer's Disease and Parkinson’s.
Drug
Methylnaltrexone
go.drugbank.com/drugs/DB06800
ApprovedInvestigational
It is also a weak CYP2D6 inhibitor. FDA approved in 2008. … Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms.
Categories: Peripheral Opioid Receptor Antagonists
Drug
Arachidonic Acid
go.drugbank.com/drugs/DB04557
ApprovedInvestigationalWithdrawn
An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. … It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. [PubChem]
Drug
Toluene
go.drugbank.com/drugs/DB11558
InvestigationalVet approved
Toluene is a colorless, liquid that is immiscible in water. It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.
Categories: Compounds used in a research, industrial, or household setting
Drug
Clobetasone
go.drugbank.com/drugs/DB13158
Approved
Clobetasone is a corticosteroid that is often employed topically as a treatment for a variety of conditions such as eczema, psoriasis, various forms of dermatitis, and also for certain ophthalmologic conditions
Categories: Corticosteroids, Moderately Potent (Group II)
Drug
NUC B1000
go.drugbank.com/drugs/DB05242
Experimental
[F3910] eiRNA is an approach to RNAi therapeutics, whereby a plasmid DNA coding for desired dsRNA is delivered to diseased cells enabling the cells to carry out dsRNA production internally thereby invoking … NUC B1000 is an expressed interfering RNA (eiRNA)- based product consisting of a plasmid DNA construct designed to produce four short interfering RNA (siRNA) molecules, formulated with a proprietary cationic-lipid
Drug
Indacaterol
go.drugbank.com/drugs/DB05039
ApprovedInvestigational
It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. … Indacaterol is provided as its maleate salt form. Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed.
Categories: Adrenergic beta-2 Receptor Agonists
Drug
Lanolin alcohols
go.drugbank.com/drugs/DB14181
Approved
It is administered as an ointment base with topical insulin and has shown to be antagonistic to wound healing. It is commonly used in allergenic testing.
Drug
Technetium Tc-99m medronate
go.drugbank.com/drugs/DB09138
ApprovedInvestigational
Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. … Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way localizes the drug to bone for delineation of areas of
Categories: Compounds used in a research, industrial, or household settingSynonyms: AN-MDP