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Displaying results 431 - 440 of 8517 in total
  1. Drug

    CoronaVac

    go.drugbank.com/drugs/DB15806
    Investigational

    It was developed by propagating the SARS-CoV-2 CN2 strain inside Vero Cells and inactivating it with B-propiolactone[A219481;A219758]. … CoronaVac, previously known as PiCoVacc, is a SARS-CoV-2 purified, inactivated, and adsorbed vaccine candidate developed by SinoVac Biotech Corporation[A219758].

  2. Drug

    Moxonidine

    go.drugbank.com/drugs/DB09242
    ApprovedInvestigationalWithdrawn

    As well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome. … It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive.

  3. Drug

    Dequalinium

    go.drugbank.com/drugs/DB04209
    Approved

    Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. … [A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain.

    Synonyms: 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride
  4. Drug

    Pivopril

    go.drugbank.com/drugs/DB19854
    Experimental

    The usage of the INN stem '-pril' in the name indicates that Pivopril is a angiotensin-converting enzyme inhibitor. Pivopril has a monoisotopic molecular weight of 329.17 Da.

  5. Drug

    Utibapril

    go.drugbank.com/drugs/DB20306
    Experimental

    The usage of the INN stem '-pril' in the name indicates that Utibapril is a angiotensin-converting enzyme inhibitor. Utibapril has a monoisotopic molecular weight of 449.2 Da.

  6. Drug

    Alacepril

    go.drugbank.com/drugs/DB21364
    Experimental

    The usage of the INN stem '-pril' in the name indicates that Alacepril is a angiotensin-converting enzyme inhibitor. Alacepril has a monoisotopic molecular weight of 406.16 Da.

  7. Drug

    Pentopril

    go.drugbank.com/drugs/DB21436
    Experimental

    The usage of the INN stem '-pril' in the name indicates that Pentopril is a angiotensin-converting enzyme inhibitor. Pentopril has a monoisotopic molecular weight of 333.16 Da.

  8. Drug

    Upanovimab

    go.drugbank.com/drugs/DB16505
    Investigational

    Upanovimab (SCTA01) was under investigation in clinical trials (NCT04683328, NCT04644185, NCT04709328 and NCT05156645) to evaluate its safety and efficacy in patients with severe COVID-19

  9. Drug

    Povidone-iodine

    go.drugbank.com/drugs/DB06812
    ApprovedInvestigational

    Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic. … During in vitro testing to demonstrate anti-bacterial activity it was found that the complex was less toxic in mice than tincture of iodine.

    Mixtures: Mas Care-pak Dexamethasone
  10. Drug

    Futibatinib

    go.drugbank.com/drugs/DB15149
    ApprovedInvestigational

    FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies … [A253193,A253198] As a novel inhibitor of FGFR, futibatinib was first approved by the FDA in September 2022 to treat different types of intrahepatic cholangiocarcinoma.