CoronaVac
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Name
- CoronaVac
- Accession Number
- DB15806
- Description
CoronaVac, previously known as PiCoVacc, is a SARS-CoV-2 purified, inactivated, and adsorbed vaccine candidate developed by SinoVac Biotech Corporation2. It was developed by propagating the SARS-CoV-2 CN2 strain inside Vero Cells and inactivating it with B-propiolactone1,2. In preclinical trials, PiCoVacc induced SARS-CoV-2-specific neutralizing antibodies in rats, mice, and the rhesus macaque. The antibodies were found to neutralize 10 representative SARS-CoV-2 strains. As of August 2020, the vaccine is being tested in numerous human clinical trials assessing its safety and immunogenicity.
- Type
- Biotech
- Groups
- Investigational
- Biologic Classification
- Vaccines
Inactivated - Synonyms
- PiCoVacc
- External IDs
- CoronaVac
Pharmacology
- Accelerate your drug discovery research with the industry’s only fully connected ADMET dataset, ideal for:Accelerate your drug discovery research with our fully connected ADMET dataset
- Indication
- Not Available
- Contraindications & Blackbox Warnings
- Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects
- Pharmacodynamics
- Not Available
- Mechanism of action
- Not Available
- Absorption
- Not Available
- Volume of distribution
- Not Available
- Protein binding
- Not Available
- Metabolism
- Not Available
- Route of elimination
- Not Available
- Half-life
- Not Available
- Clearance
- Not Available
- Adverse Effects
- Reduce medical errorsand improve treatment outcomes with our comprehensive & structured data on drug adverse effects.Reduce medical errors & improve treatment outcomes with our adverse effects data
- Toxicity
- Not Available
- Affected organisms
- Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
Chemical Identifiers
- UNII
- Not Available
- CAS number
- Not Available
References
- General References
- Gao Q, Bao L, Mao H, Wang L, Xu K, Yang M, Li Y, Zhu L, Wang N, Lv Z, Gao H, Ge X, Kan B, Hu Y, Liu J, Cai F, Jiang D, Yin Y, Qin C, Li J, Gong X, Lou X, Shi W, Wu D, Zhang H, Zhu L, Deng W, Li Y, Lu J, Li C, Wang X, Yin W, Zhang Y, Qin C: Development of an inactivated vaccine candidate for SARS-CoV-2. Science. 2020 Jul 3;369(6499):77-81. doi: 10.1126/science.abc1932. Epub 2020 May 6. [PubMed:32376603]
- Rego GNA, Nucci MP, Alves AH, Oliveira FA, Marti LC, Nucci LP, Mamani JB, Gamarra LF: Current Clinical Trials Protocols and the Global Effort for Immunization against SARS-CoV-2. Vaccines (Basel). 2020 Aug 25;8(3). pii: vaccines8030474. doi: 10.3390/vaccines8030474. [PubMed:32854391]
- Sinovac Announcement [Link]
- Vaccine in Rheus Monkeys [Link]
- External Links
- Wikipedia
- CoronaVac
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Enrolling by Invitation Prevention Coronavirus Disease 2019 (COVID‑19) 1 4 Not Yet Recruiting Health Services Research Coronavirus (SARS-CoV) / Coronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus / Vaccine Adverse Reaction 1 4 Not Yet Recruiting Prevention Chronic Liver Diseases (CLD) / Coronavirus Disease 2019 (COVID‑19) 1 4 Not Yet Recruiting Prevention Coronavirus Disease 2019 (COVID‑19) 1 4 Recruiting Prevention Acquired Immune Deficiency Syndrome (AIDS) / Coronavirus Disease 2019 (COVID‑19) / Human Immunodeficiency Virus (HIV) Infections / Immunogenicity / Rheumatic Diseases / Safety Issues 1 4 Recruiting Treatment Coronavirus Disease 2019 (COVID‑19) 1 3 Active Not Recruiting Prevention Coronavirus Disease 2019 (COVID‑19) 1 3 Not Yet Recruiting Prevention Coronavirus Disease 2019 (COVID‑19) 1 3 Recruiting Prevention Coronavirus Disease 2019 (COVID‑19) 1 3 Recruiting Prevention Coronavirus Disease 2019 (COVID‑19) / Vaccines 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created on September 05, 2020 17:17 / Updated on September 14, 2020 17:36