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Darifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalThis block reduces the urgency to urinate and so it should not be used in people with urinary retention. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Products: DARUCIL® ER 15 MGBrivoligide
go.drugbank.com/drugs/DB16116InvestigationalBrivoligide is under investigation in clinical trial NCT04104919 (Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores).
Synonyms: D(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g) (1:1), Dna, d(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g) (1:1)Flecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawn[A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [L8878,L5056] Flecainide was granted FDA approval on 31 October 1985.[L8875]
Synonyms: N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamideProducts: FLECAINIDE EGTrimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Synonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineProducts: TRIMINEURIN 40 MG/ML Z EINCyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigationalCyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977. … [A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury.
Synonyms: N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamineMixtures: RODALGIN COMPLEX TABLETASMometasone
go.drugbank.com/drugs/DB00764ApprovedInvestigationalMometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.
Products: MOMETASONE EGIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigationalrelief was observed to be 8 hours compared to 36 hours for the placebo treatment. … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema.
Categories: Drugs Used in Hereditary AngioedemaProducts: ICATIBANT EG, Icatibant STADA 30 mg Injektionslösung in einer FertigspritzeLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalIt was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). … interactions[L8606,L8600,L8615] - these characteristics make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in
Products: Levetiracetam ER, LEVETIRACETAM EGDiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalAs histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the … Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect behaviour including dopamine, norepinephrine, serotonin, acetylcholine, and opioid [A1539].
Synonyms: N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, 2-(benzhydryloxy)-N,N-dimethylethylamineMixtures: BENADRYL-E, BENADRYL EMPropafenone
go.drugbank.com/drugs/DB01182ApprovedInvestigationalAn antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Products: PROPAFENONE EG