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  1. Drug

    Pipequaline

    go.drugbank.com/drugs/DB13991
    Experimental

    Pipequaline has a similar pharmacological profile to the reported for the benzodiazepines. … However, it presents a significant set of anxiolytic properties with a very little sedative, amnestic or anticonvulsant effect.

  2. Drug

    Deramciclane

    go.drugbank.com/drugs/DB06512
    Investigational

    Deramciclane (EGIS-3886) is used for the treatment of a number of anxiety disorders. … Deramciclane differs from other anti anxiety medications in that it is not a benzodiazepine and so has a different structure and target.

  3. Drug

    PB127

    go.drugbank.com/drugs/DB06208
    Investigational

  4. Drug

    Cefovecin

    go.drugbank.com/drugs/DB11505
    ExperimentalVet approved

    Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. … It is the first single-dose injectable antibiotic for dogs and cats that assures owner compliance with dosing for the animal.

  5. Drug

    Pentoxyverine

    go.drugbank.com/drugs/DB11186
    ApprovedWithdrawn

    Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and local anesthetic properties.

    Mixtures: Pancold AProducts: PENTOXYVERIN AL 19MG/ML, PENTOXYVERIN AL 1.35 MG/ML
  6. Drug

    TPMPA

    go.drugbank.com/drugs/DB16754
    Experimental

    TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA<sub>C</sub> receptors (also known as GABA-ρ or GABA<sub>A-ρ</sub> receptors). … [A245308,A245313] TPMPA is used as a pharmacological probe for the investigation of GABA<sub>C</sub> receptor function.[A245313]

  7. Drug

    Asimadoline

    go.drugbank.com/drugs/DB05104
    Investigational

    It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases. … Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist.

  8. Drug

    MD05

    go.drugbank.com/drugs/DB06375
    Investigational

    MD05 is a beta-tricalcium phosphate (beta-TCP) coated with recombinant human growth/differentiation factor-5 (rhGDF-5).

  9. Drug

    Glembatumumab vedotin

    go.drugbank.com/drugs/DB05996
    Investigational

    A conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast cancer.

  10. Drug

    GPI-1485

    go.drugbank.com/drugs/DB05814
    Investigational

    GPI 1485 is a product candidate that belongs to a class of small molecule compounds called neuroimmunophilin ligands. … GPI 1485 is being studied in phase 2 clinical trials for the treatment of Parkinson's disease and post-prostatectomy erectile dysfunction and in pre-clinical development for HIV related dementia and neuropathy