Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- MD05
- DrugBank Accession Number
- DB06375
- Background
MD05 is a beta-tricalcium phosphate (beta-TCP) coated with recombinant human growth/differentiation factor-5 (rhGDF-5).
- Type
- Small Molecule
- Groups
- Investigational
- Synonyms
- Not Available
- External IDs
- MD 05
- MD-05
- MD05
Pharmacology
- Indication
Investigated for use/treatment in periodontal disease.
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Not Available
- Mechanism of action
MD05 has two components: the recombinant growth factor, rhGDF-5, a naturally occurring human protein that acts by promoting the growth of bone and the inorganic carrier, beta-Tricalcium phosphate (beta-TCP). Beta-TCP is a synthetic calcium phosphate biomaterial, which acts as a scaffold and space maintainer for new bone ingrowth. It is a well accepted biomaterial for bone augmentation in dentistry and orthopaedic surgery such as e.g. spinal fusion. Growth factor and carrier material are combined by Scil’s proprietary technology, which allows for a homogeneous distribution of the growth factor on the carrier and maintenance of structure and function of the protein and avoidance of its aggregation.
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Not Available
- CAS number
- Not Available
- InChI Key
- Not Available
- InChI
- Not Available
- IUPAC Name
- Not Available
- SMILES
- Not Available
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at March 19, 2008 16:28 / Updated at August 16, 2024 10:59