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Cretostimogene grenadenorepvec
go.drugbank.com/drugs/DB05148InvestigationalCG0070 is investigated in clinical trials for treating bladder cancer. CG0070 is a solid. … It has been engineered to secrete GM-CSF, an immune stimulating hormone, which also serves as the adjuvant in cancer immunotherapy.
Atl146e
go.drugbank.com/drugs/DB05191InvestigationalATL146e is an anti-inflammatory compounds which is an agonist of A2A adenosine receptors.
Categories: Adenosine A receptor agonists, Heterocyclic Compounds, 2-RingFK352B
go.drugbank.com/drugs/DB06484ExperimentalFK352B is a adenosine A1 antagonist that is developed for the treatment of dialysis-induced hypotension.
Synonyms: 2-((2R)-1-((2E)-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)PROP-2-ENOYL)PIPERIDIN-2-YL)ACETIC ACID, 2-PIPERIDINEACETIC ACID, 1-((2E)-1-OXO-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)-2-PROPEN-1-YL)-, (2R)-Categories: Heterocyclic Compounds, 1-RingXP21279
go.drugbank.com/drugs/DB06319InvestigationalXP21279 is a prodrug of [Levodopa], a dopamine precursor used in the management of Parkinson's disease. … XP21279 was under investigation in clinical trial NCT00914602 (An Exploratory Study of XP21279 (With Lodosyn®) and Sinemet® in Parkinson's Disease Subjects), administered in combination with [Carbidopa
Amitraz
go.drugbank.com/drugs/DB11373ExperimentalVet approvedAmitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. … Amitraz presents a lower effect in mammals and thus, it is widely used in the treatment of mite- or tick-infestation of dogs.
Synonyms: N,N'-(methyliminodimethylidyne)bis-2,4-xylidine, 1,5-di(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-dieneCategories: Compounds used in a research, industrial, or household setting, Adrenergic alpha-2 Receptor AgonistsGirentuximab
go.drugbank.com/drugs/DB05304InvestigationalGirentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
RI 624
go.drugbank.com/drugs/DB05892ExperimentalRI 624 is being developed by Rinat and is currently in Phase I clinical trials. … RI 624 is a novel humanized monoclonal antibody that blocks nerve growth factor (NGF), a key mediator of acute and chronic pain.
Cryptenamine
go.drugbank.com/drugs/DB00785ApprovedIt has been used in the treatment of hypertension but has largely been replaced by drugs with fewer adverse effects. … Cryptenamine is a mixture of closely related hypotensive alkaloids from Veratrum album (Liliaceae).
Categories: Heterocyclic Compounds with 4 or More RingsAcifluorfen
go.drugbank.com/drugs/DB07338ExperimentalAcifluorfen is a protoporphyrinogen oxidase inhibitor.
Categories: Compounds used in a research, industrial, or household settingCX-051869
go.drugbank.com/drugs/DB31656ApprovedCX-051869 is a COVID-19 mRNA vaccine encoding the pre-fusion stabilized Spike glycoprotein (S) of the SARS-CoV-2 Omicron variant lineage LP.8.1. … It is the active ingredient of the 2025-2026 formulation of Moderna's Spikevax vaccine.[L40074]