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Carbon dioxide
go.drugbank.com/drugs/DB09157ApprovedInvestigationalVet approvedMedical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may be used in different situations, e.g. … Carbon dioxide is a colorless, odorless gas vital to life on Earth. This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two oxygen atoms.
Mixtures: Carbon Dioxide 1% W Air, Carbon Dioxide 1% W OxygenCategories: X-Ray Contrast ActivityIodoform
go.drugbank.com/drugs/DB13813ApprovedInvestigationalVet approvedWithdrawnIt is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions [A32890]. … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry.
Products: Iodoform Packing Strip 5% W/w, Iodoform Nugauze Packing Strip 5%Tiopronin
go.drugbank.com/drugs/DB06823ApprovedIt is similar to d-penicillamine in use and efficacy, but offers the advantage of far less adverse effects. … It has been investigated for use in the treatment of arthritis and as a neuroprotective agent in aneurysmal subarachnoid hemorrhage.
Categories: N-substituted GlycinesProducts: Thiola ECMomelotinib
go.drugbank.com/drugs/DB11763ApprovedInvestigationalMomelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding. … MF includes primary MF (PMF), post-polycythemia vera (PV) MF, and post-essential thrombocythemia (ET) MF. Clinical manifestations of MF include anemia and thrombocytosis.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesSynonyms: N-(CYANOMETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDEDoxercalciferol
go.drugbank.com/drugs/DB06410ApprovedInvestigationalDoxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin … or Stage 4 chronic kidney disease.
Categories: Vitamin D and AnaloguesSynonyms: 1-Hydroxyvitamin D2, 1-HydroxyergocalciferolCardiolipin Biosynthesis CL(10:0/18:2(9Z,11Z)/i-20:0/i-20:0)
smpdb.ca/view/SMP0178843MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.
Cevimeline
go.drugbank.com/drugs/DB00185ApprovedCevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. … It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Synonyms: 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidineCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesXanomeline
go.drugbank.com/drugs/DB15357ApprovedInvestigationaldiscovered that M1 and M4 muscarinic acetylcholine receptors are highly expressed in brain regions that are implicated in cognition. … [L51713] It is approved as part of a combination product alongside [trospium], a muscarinic antagonist that acts primarily on peripheral muscarinic receptors in order to mitigate the risk and severity
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsDe Novo Triacylglycerol Biosynthesis TG(10:0/12:0/i-20:0)
smpdb.ca/view/SMP0031731MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...
De Novo Triacylglycerol Biosynthesis TG(10:0/18:0/i-20:0)
smpdb.ca/view/SMP0031833MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...