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Displaying results 4431 - 4440 of 6951 in total
  1. Drug

    Larazotide

    go.drugbank.com/drugs/DB05645
    Investigational

    An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.

  2. Drug

    ABX1100

    go.drugbank.com/drugs/DB17655
    Investigational

    It was first developed by Aro Biotherapeutics and is being investigated for the treatment of Pompe disease.[L45978] … ABX1100 is an investigational Centyrin-siRNA conjugate that targets the Gys1 gene, which encodes glycogen synthase 1 (Gys1), an enzyme that is responsible for glycogen synthesis in the muscle.

  3. Drug

    UB-612

    go.drugbank.com/drugs/DB16444
    Investigational

    In rats, toxicity studies have so far shown favourable safety for this vaccine[L30653, L30658], Phase 1 trial is currently ongoing in Taiwan (NCT04545749). … In addition, the vaccine contains a proprietary peptide UBITh®1a for enhanced immunogenicity, five identified peptides with Th or CTL epitopes to improve peptide solubility, and aluminum phosphate adjuvant

  4. Drug

    Brecanavir

    go.drugbank.com/drugs/DB04887
    Investigational

    Brecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV. … In December of 2006 GSK announced a decision to discontinue the development of brecanavir for the treatment of HIV. The decision was based on issues regarding the formulation of the drug.

  5. Drug

    Mitiglinide

    go.drugbank.com/drugs/DB01252
    Investigational

    Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.

  6. Drug

    Zaltoprofen

    go.drugbank.com/drugs/DB06737
    Investigational

    A non-steroidal anti-inflammatory drug approved for use in Japan in 1993.

  7. Drug

    Olaptesed Pegol

    go.drugbank.com/drugs/DB11707
    Investigational

    Olaptesed Pegol has been investigated for the treatment of Hematopoietic Stem Cell Transplantation.

  8. Drug

    Angiotensin 1-7

    go.drugbank.com/drugs/DB11720
    Investigational

    TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities.

  9. Drug

    Latrepirdine

    go.drugbank.com/drugs/DB11725
    Investigational

    Latrepirdine has been investigated for the treatment of Alzheimer's Disease and Huntington's Disease.

  10. Drug

    Alvelestat

    go.drugbank.com/drugs/DB11863
    Investigational

    Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.