Angiotensin 1-7

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DB11720InvestigationalSmall molecule

TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities.

Mechanism: Pharmacologically active on Proto-oncogene Mas
Curator reviewed
Formula / weight: C₄₁H₆₂N₁₂O₁₁ · 899.02 g/mol (avg)
Also known as: Angiotensin (1-7) · Angiotensin I (1-7) · Angiotensin II (1-7) heptapeptide · Angiotensin-(1-7)
Code names: TXA-127 · USB002

Resolves to

Compound

UNIIIJ3FUK8MOFCAS51833-78-4ChEMBLCHEMBL3545347ChEBI55438PubChem123805

Structure

InChIKeyPVHLMTREZMEJCG-GDTLVBQBSA-NSMILES

[H][C@](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(O)=O

Targets

P04201MAS1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

634Drug interactionsStructured to mechanism, not free text

32Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Angiotensin 1-7, and which of those have an active Phase 3 trial?

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