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Potrasertib
go.drugbank.com/drugs/DB21682ExperimentalPotrasertib has a monoisotopic molecular weight of 564.19 Da.
Sodium oxybate
go.drugbank.com/drugs/DB09072ApprovedInvestigational[A251430] Due to its physiological effects, sodium oxybate is associated with a risk for substance misuse and abuse.
Fomivirsen
go.drugbank.com/drugs/DB06759ApprovedWithdrawnThe drug was withdrawn by the FDA because while there was a high unmet need for drugs to treat CMV when the drug was initially discovered and developed due to the CMV arising in people with AIDS, the development
Vonoprazan
go.drugbank.com/drugs/DB11739ApprovedInvestigationalUnlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations.
Levamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117, A178123] Levamisole was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis.
Tolbutamide
go.drugbank.com/drugs/DB01124ApprovedDue to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk.
Isavuconazonium
go.drugbank.com/drugs/DB06636ApprovedInvestigationalDue to low solubility in water of isavuconazole on its own, the isovuconazonium formulation is favorable as it has high solubility in water and allows for intravenous administration.
Histrelin
go.drugbank.com/drugs/DB06788ApprovedInvestigationalWithdrawn[L41710] GnRH agonists are the first line of treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and the concentration of sex steroids.
Synonyms: [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamideLotrafiban
go.drugbank.com/drugs/DB20872ExperimentalLotrafiban has a monoisotopic molecular weight of 428.24 Da.
Tanogitran
go.drugbank.com/drugs/DB21367InvestigationalTanogitran has a monoisotopic molecular weight of 477.25 Da.