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Displaying results 4451 - 4460 of 10000 in total
  1. Drug

    Axitinib

    go.drugbank.com/drugs/DB06626
    ApprovedInvestigational

    It is reported to exhibit potency that is 50-450 times higher than that of the first generation VEGFR inhibitors.[L6676] Axitinib is an indazole derivative. … [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
  2. Drug

    Equilin

    go.drugbank.com/drugs/DB02187
    Experimental

    It has a total of four double bonds in the A- and B-ring. High concentration of equilin is found in the urine of pregnant mares.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 7-Dehydroestrone, 1,3,5,7-Estratetraen-3-ol-17-one
  3. Drug

    Sesame oil

    go.drugbank.com/drugs/DB11172
    ApprovedNutraceutical

    Sesame oil is reported to possess antioxidant, antiaging, antihypertensive, immunoregulatory and anticancer properties. It has also shown to accelerate alcohol decomposition in the liver [A27257]. … Sesame oil is considered an indirect additive used in food cotact substances by the FDA.

    Synonyms: 芝麻油
  4. Drug

    2,5-Dimethoxy-4-ethylamphetamine

    go.drugbank.com/drugs/DB01467
    ExperimentalIllicit

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 2,5-Dimethoxy-4-ethylamphetamine
  5. Drug

    Adefovir dipivoxil

    go.drugbank.com/drugs/DB00718
    Approved

    It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir. … of hepatitis B.

    Categories: Heterocyclic Compounds, 2-Ring, Hepatitis B Virus Nucleoside Analog Reverse Transcriptase InhibitorInternational brands: A Di Xian, A Gan Ding
  6. Drug

    Phosphate ion

    go.drugbank.com/drugs/DB14523
    Investigational

    Mixtures: PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1000 ML, PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1500 ML
  7. Drug

    Cemivameran

    go.drugbank.com/drugs/DB19415
    Approved

    Cemivameran (BNT162b2 Omicron (KP.2)) is COVID-19 mRNA vaccine encoding the viral spike (S) glycoprotein of SARS-CoV-2 Omicron variant lineage KP.2. … It is the active ingredient in the 2024-2025 formulation of Pfizer-BioNTech's Comirnaty vaccine.[L36030]

    Synonyms: BNT162b2 Omicron (KP.2)
  8. Drug

    MW33

    go.drugbank.com/drugs/DB16358
    Experimental

    MW33 is a recombinant fully human antibody to SARS-CoV-2. … [L27411] This antibody injection is currently being investigated against COVID-19 in the clinical trial NCT04533048 (A Clinical Study to Evaluate MW33 Injection).

  9. Drug

    MBO7133

    go.drugbank.com/drugs/DB04999
    Experimental

    However, araC is only slowly converted to araCTP in the liver or in primary liver tumors due to low levels of an enzyme in the liver that is required for the conversion of araC to araCMP, the first step … MB07133 is a HepDirect prodrug of an activated form of cytarabine (araC), an anti-cancer drug that is used to treat leukemia but is ineffective against primary liver cancer.

  10. Drug

    Sarracenia Purpurea

    go.drugbank.com/drugs/DB13965
    ApprovedWithdrawn

    _Sarracenia purpurea_, commonly known as the purple pitcher plant, northern pitcher plant, turtle socks, or side-saddle flower, is a perennial carnivorous plant in the family _Sarraceniaceae_. … It was used as an injectable pain reliever and during the 19th century, _Sarracenia purpurea_ was used as a treatment of smallpox [A32509].

    Synonyms: Sarracenia purpurea l.Products: P-Bloc