Phosphate ion

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name

Phosphate ion

DrugBank Accession Number

DB14523

Background

Not Available

Type

Small Molecule

Groups

Experimental

Structure

Similar Structures

Weight: Average: 94.9714
Monoisotopic: 94.95342
Chemical Formula: O₄P

Synonyms

Orthophosphate
Phosphate

Pharmacology

Indication: Not Available
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Interactions

Drug Interactions

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Drug	Interaction
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Aluminum hydroxide	Aluminum hydroxide can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric ammonium citrate	Ferric ammonium citrate can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose	Ferric carboxymaltose can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation	Ferric cation can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric maltol	Ferric maltol can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric sulfate	Ferric sulfate can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferrous bisglycinate	Ferrous bisglycinate can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferrous fumarate	Ferrous fumarate can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferrous gluconate	Ferrous gluconate can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferrous succinate	Ferrous succinate can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.

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Food Interactions

Not Available

Products

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Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Liquidguard	Liquid	2.5 g/100mL	Topical	Nano Care Deutschland AG	2020-03-30	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1250 ML	Phosphate ion (15 mmol) + Acetate (45 mmol) + Alanine (5.82 g) + Arginine (3.24 g) + Aspartic acid (1.8 g) + Calcium (4 mmol) + Calcium chloride dihydrate (0.588 g) + Chlorine (45 mmol) + D-glucose (150 g) + Glutamic acid (4.21 g) + Glycine (1.98 g) + Histidine (1.5 g) + Isoleucine (2.82 g) + Leucine (3.76 g) + Lysine (2.73 g) + Magnesium (4 mmol) + Magnesium acetate tetrahydrate (0.858 g) + Medium-chain triglycerides (25 g) + Methionine (2.35 g) + Phenylalanine (4.21 g) + Potassium (35 mmol) + Potassium acetate (3.434 g) + Proline (4.08 g) + Serine (3.6 g) + Sodium acetate trihydrate (0.277 g) + Sodium cation (50 mmol) + Sodium chloride (0.503 g) + Sodium hydroxide (0.976 g) + Sodium phosphate, monobasic, dihydrate (2.34 g) + Soybean oil (25 g) + Threonine (2.18 g) + Tryptophan (0.68 g) + Valine (3.12 g) + Zinc (0.03 mmol) + Zinc acetate dihydrate (6.58 mg)	Injection, emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2020-08-14	2018-10-03
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1870 ML	Phosphate ion (22.5 mmol) + Acetate (67.5 mmol) + Alanine (8.73 g) + Arginine (4.86 g) + Aspartic acid (2.7 g) + Calcium (6 mmol) + Calcium chloride dihydrate (0.882 g) + Chlorine (67.5 mmol) + D-glucose (225 g) + Glutamic acid (6.32 g) + Glycine (2.97 g) + Histidine (2.25 g) + Isoleucine (4.23 g) + Leucine (5.64 g) + Lysine (4.1 g) + Magnesium (6 mmol) + Magnesium acetate tetrahydrate (1.287 g) + Medium-chain triglycerides (37.5 g) + Methionine (3.53 g) + Phenylalanine (6.32 g) + Potassium (52.5 mmol) + Potassium acetate (5.151 g) + Proline (6.12 g) + Serine (5.4 g) + Sodium acetate trihydrate (0.416 g) + Sodium cation (75 mmol) + Sodium chloride (0.755 g) + Sodium hydroxide (1.464 g) + Sodium phosphate, monobasic, dihydrate (3.51 g) + Soybean oil (37.5 g) + Threonine (3.27 g) + Tryptophan (1.02 g) + Valine (4.68 g) + Zinc (0.045 mmol) + Zinc acetate dihydrate (9.87 mg)	Injection, emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2020-08-14	2018-10-03
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 2500 ML	Phosphate ion (30 mmol) + Acetate (90 mmol) + Alanine (11.64 g) + Arginine (6.48 g) + Aspartic acid (3.6 g) + Calcium (8 mmol) + Calcium chloride dihydrate (1.176 g) + Chlorine (90 mmol) + D-glucose (300 g) + Glutamic acid (8.42 g) + Glycine (3.96 g) + Histidine (3 g) + Isoleucine (5.64 g) + Leucine (7.52 g) + Lysine (5.46 g) + Magnesium (8 mmol) + Magnesium acetate tetrahydrate (1.716 g) + Medium-chain triglycerides (50 g) + Methionine (4.7 g) + Phenylalanine (8.42 g) + Potassium (70 mmol) + Potassium acetate (6.868 g) + Proline (8.16 g) + Serine (7.2 g) + Sodium acetate trihydrate (0.554 g) + Sodium cation (100 mmol) + Sodium chloride (1.006 g) + Sodium hydroxide (1.952 g) + Sodium phosphate, monobasic, dihydrate (4.68 g) + Soybean oil (50 g) + Threonine (4.36 g) + Tryptophan (1.36 g) + Valine (6.24 g) + Zinc (0.06 mmol) + Zinc acetate dihydrate (13.16 mg)	Injection, emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2020-08-14	2018-10-03
NUTRIFLEX LIPID SPECIAL INTRAVENOZ INFUZYONLUK EMULSIYON, 1250 ML	Phosphate ion (15 mmol) + Acetate (45 mmol) + Alanine (5.82 g) + Arginine (3.24 g) + Aspartic acid (1.8 g) + Calcium (4 mmol) + Calcium chloride dihydrate (0.588 g) + Chlorine (45 mmol) + D-glucose (150 g) + Glutamic acid (4.21 g) + Glutamic acid (1.98 g) + Histidine (2.03 g) + Isoleucine (2.82 g) + Leucine (3.76 g) + Lysine (2.73 g) + Magnesium (4 mmol) + Magnesium acetate tetrahydrate (0.858 g) + Medium-chain triglycerides (25 g) + Methionine (2.35 g) + Phenylalanine (4.21 g) + Potassium (35 mmol) + Potassium acetate (3.434 g) + Proline (4.08 g) + Serine (3.6 g) + Sodium acetate trihydrate (0.277 g) + Sodium cation (50 mmol) + Sodium chloride (0.503 g) + Sodium hydroxide (0.976 g) + Sodium phosphate, monobasic, dihydrate (2.34 g) + Soybean oil (25 g) + Threonine (2.18 g) + Tryptophan (0.68 g) + Valine (3.12 g) + Zinc (0.03 mmol) + Zinc acetate dihydrate (6.58 mg)	Emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2020-08-14	2018-10-03
NUTRIFLEX LIPID SPECIAL INTRAVENOZ INFUZYONLUK EMULSIYON, 1875 ML	Phosphate ion (22.5 mmol) + Acetate (67.5 mmol) + Alanine (8.73 g) + Arginine (4.86 g) + Aspartic acid (2.7 g) + Calcium (6 mmol) + Calcium chloride dihydrate (0.882 g) + Chlorine (67.5 mmol) + D-glucose (225 g) + Glutamic acid (6.32 g) + Glutamic acid (2.97 g) + Histidine (3.05 g) + Isoleucine (4.23 g) + Leucine (5.64 g) + Lysine (4.1 g) + Magnesium (6 mmol) + Magnesium acetate tetrahydrate (1.287 g) + Medium-chain triglycerides (37.5 g) + Methionine (3.53 g) + Phenylalanine (6.32 g) + Potassium (52.5 mmol) + Potassium acetate (5.151 g) + Proline (6.12 g) + Serine (5.4 g) + Sodium acetate trihydrate (0.416 g) + Sodium cation (75 mmol) + Sodium chloride (0.755 g) + Sodium hydroxide (1.464 g) + Sodium phosphate, monobasic, dihydrate (3.51 g) + Soybean oil (37.5 g) + Threonine (3.27 g) + Tryptophan (1.02 g) + Valine (4.68 g) + Zinc (0.045 mmol) + Zinc acetate dihydrate (9.87 mg)	Emulsion	Intravenous	B.BRAUN MEDİKAL DIŞ TİC. A.Ş.	2020-08-14	2018-10-03
PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1000 ML	Phosphate ion (8.5 mmol) + Acetate (27 mmol) + Alanine (3.66 g) + Arginine (2.48 g) + Aspartic acid (0.73 g) + Calcium (2 mmol) + Calcium chloride dihydrate (0.3 g) + Chloride ion (24 mmol) + D-glucose (75 g) + Glutamic acid (1.26 g) + Glycine (1.76 g) + Histidine (1.51 g) + Isoleucine (1.26 g) + Leucine (1.76 g) + Lysine (1.99 g) + Magnesium (2.2 mmol) + Magnesium chloride hexahydrate (0.45 g) + Methionine (1.26 g) + Olive oil (6 g) + Phenylalanine (1.76 g) + Potassium (16 mmol) + Potassium chloride (1.19 g) + Proline (1.51 g) + Serine (1 g) + Sodium acetate trihydrate (1.16 g) + Sodium cation (21 mmol) + Sodium glycerophosphate hydrate (1.91 g) + Soybean oil (6 g) + Threonine (1.26 g) + Tryptophan (0.42 g) + Tyrosine (0.06 g) + Valine (1.62 g)	Injection, emulsion	Intravenous	EİP ECZACIBAŞI İLAÇ PAZARLAMA A.Ş.	2020-08-14	Not applicable
PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1500 ML	Phosphate ion (12.7 mmol) + Acetate (41 mmol) + Alanine (5.5 g) + Arginine (3.72 g) + Aspartic acid (1.1 g) + Calcium (3 mmol) + Calcium chloride dihydrate (0.44 g) + Chloride ion (37 mmol) + D-glucose (112.5 g) + Glutamic acid (1.9 g) + Glycine (2.63 g) + Histidine (2.26 g) + Isoleucine (1.9 g) + Leucine (2.63 g) + Lysine (2.99 g) + Magnesium (3.3 mmol) + Magnesium chloride hexahydrate (0.67 g) + Methionine (1.9 g) + Olive oil (9 g) + Phenylalanine (2.63 g) + Potassium (24 mmol) + Potassium chloride (1.79 g) + Proline (2.26 g) + Serine (1.5 g) + Sodium acetate trihydrate (1.73 g) + Sodium cation (31.5 mmol) + Sodium glycerophosphate hydrate (2.87 g) + Soybean oil (9 g) + Threonine (1.9 g) + Tryptophan (0.64 g) + Tyrosine (0.1 g) + Valine (2.43 g)	Injection, emulsion	Intravenous	EİP ECZACIBAŞI İLAÇ PAZARLAMA A.Ş.	2020-08-14	Not applicable
PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 2000 ML	Phosphate ion (17 mmol) + Acetate (55 mmol) + Alanine (7.33 g) + Arginine (4.96 g) + Aspartic acid (1.46 g) + Calcium (4 mmol) + Calcium chloride dihydrate (0.59 g) + Chloride ion (49 mmol) + D-glucose (150 g) + Glutamic acid (2.53 g) + Glycine (3.51 g) + Histidine (3.02 g) + Isoleucine (2.53 g) + Leucine (3.51 g) + Lysine (3.98 g) + Magnesium (4.4 mmol) + Magnesium chloride hexahydrate (0.9 g) + Methionine (2.53 g) + Olive oil (12 g) + Phenylalanine (3.51 g) + Potassium (32 mmol) + Potassium chloride (2.38 g) + Proline (3.02 g) + Serine (2 g) + Sodium acetate trihydrate (2.31 g) + Sodium cation (42 mmol) + Sodium glycerophosphate hydrate (3.82 g) + Soybean oil (12 g) + Threonine (2.53 g) + Tryptophan (0.85 g) + Tyrosine (0.13 g) + Valine (3.24 g)	Injection, emulsion	Intravenous	EİP ECZACIBAŞI İLAÇ PAZARLAMA A.Ş.	2020-08-14	Not applicable
PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 2500 ML	Phosphate ion (21.2 mmol) + Acetate (69 mmol) + Alanine (9.16 g) + Arginine (6.2 g) + Aspartic acid (1.83 g) + Calcium (5 mmol) + Calcium chloride dihydrate (0.74 g) + Chloride ion (61 mmol) + D-glucose (187.5 g) + Glutamic acid (3.16 g) + Glycine (4.39 g) + Histidine (3.77 g) + Isoleucine (3.16 g) + Leucine (4.39 g) + Lysine (4.98 g) + Magnesium (5.5 mmol) + Magnesium chloride hexahydrate (1.12 g) + Methionine (3.16 g) + Olive oil (15 g) + Phenylalanine (4.39 g) + Potassium (40 mmol) + Potassium chloride (2.98 g) + Proline (3.77 g) + Serine (2.5 g) + Sodium acetate trihydrate (2.89 g) + Sodium cation (52.5 mmol) + Sodium glycerophosphate hydrate (4.78 g) + Soybean oil (15 g) + Threonine (3.16 g) + Tryptophan (1.06 g) + Tyrosine (0.16 g) + Valine (4.05 g)	Injection, emulsion	Intravenous	EİP ECZACIBAŞI İLAÇ PAZARLAMA A.Ş.	2020-08-14	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
Liquidguard	Phosphate ion (2.5 g/100mL)	Liquid	Topical	Nano Care Deutschland AG	2020-03-30	Not applicable

Chemical Identifiers

UNII: NK08V8K8HR
CAS number: 14265-44-2
InChI Key: NBIIXXVUZAFLBC-UHFFFAOYSA-K
InChI: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
IUPAC Name: phosphate
SMILES: [O-]P([O-])([O-])=O

References

General References

Not Available

External Links

Human Metabolome Database: HMDB0001429
ChemSpider: 1032
BindingDB: 50155537
RxNav: 486961
ChEBI: 18367
PDBe Ligand: PO4
Wikipedia: Phosphate

PDB Entries

117e / 13pk / 151l / 1914 / 1a2y / 1a40 / 1a6q / 1a7k / 1a9o / 1a9p …

show 6866 more

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count
0	Recruiting	Treatment	HHRH / Hypercalciuria / Hypophosphatemia / Rickets / X-linked Hypophosphatemia (XLH)	1
Not Available	Completed	Other	Chronic Kidney Disease (CKD)	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Liquid	Topical	2.5 g/100mL
Injection, emulsion	Intravenous
Emulsion	Intravenous

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
logP	-1	ChemAxon
pKa (Strongest Acidic)	1.8	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	86.25 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	11.29 m³·mol^-1	ChemAxon
Polarizability	4.93 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	1	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Spectrum	Spectrum Type	Splash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)	Predicted LC-MS/MS	splash10-0002-9000000000-5fa0319f90e59fa29fd6
Predicted MS/MS Spectrum - 20V, Positive (Annotated)	Predicted LC-MS/MS	splash10-0002-9000000000-4d04c52017553b8714c8
Predicted MS/MS Spectrum - 40V, Positive (Annotated)	Predicted LC-MS/MS	splash10-000t-9000000000-cb8134bc14f66db5b0bb
Predicted MS/MS Spectrum - 10V, Negative (Annotated)	Predicted LC-MS/MS	splash10-0006-9000000000-755717f229a32cd2dccf
Predicted MS/MS Spectrum - 20V, Negative (Annotated)	Predicted LC-MS/MS	splash10-0006-9000000000-003ecbaa2a45f587b953
Predicted MS/MS Spectrum - 40V, Negative (Annotated)	Predicted LC-MS/MS	splash10-0006-9000000000-d32bf6727c65f9ec0f1d

Drug created at July 12, 2018 19:12 / Updated at June 12, 2020 16:53

Phosphate ion

Identification

Structure for Phosphate ion (DB14523)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra