Phosphate ion

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Phosphate ion
DrugBank Accession Number
DB14523
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 94.9714
Monoisotopic: 94.95342
Chemical Formula
O4P
Synonyms
  • Orthophosphate
  • Phosphate

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
Aluminum hydroxideAluminum hydroxide can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric ammonium citrateFerric ammonium citrate can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltoseFerric carboxymaltose can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cationFerric cation can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric maltolFerric maltol can cause a decrease in the absorption of Phosphate ion resulting in a reduced serum concentration and potentially a decrease in efficacy.
Food Interactions
Not Available

Products

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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
LiquidguardLiquid2.5 g/100mLTopicalNano Care Deutschland AG2020-03-30Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1250 MLPhosphate ion (15 mmol) + Acetate (45 mmol) + Alanine (5.82 g) + Arginine (3.24 g) + Aspartic acid (1.8 g) + Calcium (4 mmol) + Calcium chloride dihydrate (0.588 g) + Chlorine (45 mmol) + D-glucose (150 g) + Glutamic acid (4.21 g) + Glycine (1.98 g) + Histidine (1.5 g) + Isoleucine (2.82 g) + Leucine (3.76 g) + Lysine (2.73 g) + Magnesium (4 mmol) + Magnesium acetate tetrahydrate (0.858 g) + Medium-chain triglycerides (25 g) + Methionine (2.35 g) + Phenylalanine (4.21 g) + Potassium (35 mmol) + Potassium acetate (3.434 g) + Proline (4.08 g) + Serine (3.6 g) + Sodium acetate trihydrate (0.277 g) + Sodium cation (50 mmol) + Sodium chloride (0.503 g) + Sodium hydroxide (0.976 g) + Sodium phosphate, monobasic, dihydrate (2.34 g) + Soybean oil (25 g) + Threonine (2.18 g) + Tryptophan (0.68 g) + Valine (3.12 g) + Zinc (0.03 mmol) + Zinc acetate dihydrate (6.58 mg)Injection, emulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2005-11-162018-10-03Turkey flag
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1870 MLPhosphate ion (22.5 mmol) + Acetate (67.5 mmol) + Alanine (8.73 g) + Arginine (4.86 g) + Aspartic acid (2.7 g) + Calcium (6 mmol) + Calcium chloride dihydrate (0.882 g) + Chlorine (67.5 mmol) + D-glucose (225 g) + Glutamic acid (6.32 g) + Glycine (2.97 g) + Histidine (2.25 g) + Isoleucine (4.23 g) + Leucine (5.64 g) + Lysine (4.1 g) + Magnesium (6 mmol) + Magnesium acetate tetrahydrate (1.287 g) + Medium-chain triglycerides (37.5 g) + Methionine (3.53 g) + Phenylalanine (6.32 g) + Potassium (52.5 mmol) + Potassium acetate (5.151 g) + Proline (6.12 g) + Serine (5.4 g) + Sodium acetate trihydrate (0.416 g) + Sodium cation (75 mmol) + Sodium chloride (0.755 g) + Sodium hydroxide (1.464 g) + Sodium phosphate, monobasic, dihydrate (3.51 g) + Soybean oil (37.5 g) + Threonine (3.27 g) + Tryptophan (1.02 g) + Valine (4.68 g) + Zinc (0.045 mmol) + Zinc acetate dihydrate (9.87 mg)Injection, emulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2005-11-162018-10-03Turkey flag
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 2500 MLPhosphate ion (30 mmol) + Acetate (90 mmol) + Alanine (11.64 g) + Arginine (6.48 g) + Aspartic acid (3.6 g) + Calcium (8 mmol) + Calcium chloride dihydrate (1.176 g) + Chlorine (90 mmol) + D-glucose (300 g) + Glutamic acid (8.42 g) + Glycine (3.96 g) + Histidine (3 g) + Isoleucine (5.64 g) + Leucine (7.52 g) + Lysine (5.46 g) + Magnesium (8 mmol) + Magnesium acetate tetrahydrate (1.716 g) + Medium-chain triglycerides (50 g) + Methionine (4.7 g) + Phenylalanine (8.42 g) + Potassium (70 mmol) + Potassium acetate (6.868 g) + Proline (8.16 g) + Serine (7.2 g) + Sodium acetate trihydrate (0.554 g) + Sodium cation (100 mmol) + Sodium chloride (1.006 g) + Sodium hydroxide (1.952 g) + Sodium phosphate, monobasic, dihydrate (4.68 g) + Soybean oil (50 g) + Threonine (4.36 g) + Tryptophan (1.36 g) + Valine (6.24 g) + Zinc (0.06 mmol) + Zinc acetate dihydrate (13.16 mg)Injection, emulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2020-08-142018-10-03Turkey flag
NUTRIFLEX LIPID SPECIAL INTRAVENOZ INFUZYONLUK EMULSIYON, 1250 MLPhosphate ion (15 mmol) + Acetate (45 mmol) + Alanine (5.82 g) + Arginine (3.24 g) + Aspartic acid (1.8 g) + Calcium (4 mmol) + Calcium chloride dihydrate (0.588 g) + Chlorine (45 mmol) + D-glucose (150 g) + Glutamic acid (4.21 g) + Glutamic acid (1.98 g) + Histidine (2.03 g) + Isoleucine (2.82 g) + Leucine (3.76 g) + Lysine (2.73 g) + Magnesium (4 mmol) + Magnesium acetate tetrahydrate (0.858 g) + Medium-chain triglycerides (25 g) + Methionine (2.35 g) + Phenylalanine (4.21 g) + Potassium (35 mmol) + Potassium acetate (3.434 g) + Proline (4.08 g) + Serine (3.6 g) + Sodium acetate trihydrate (0.277 g) + Sodium cation (50 mmol) + Sodium chloride (0.503 g) + Sodium hydroxide (0.976 g) + Sodium phosphate, monobasic, dihydrate (2.34 g) + Soybean oil (25 g) + Threonine (2.18 g) + Tryptophan (0.68 g) + Valine (3.12 g) + Zinc (0.03 mmol) + Zinc acetate dihydrate (6.58 mg)EmulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2007-07-032018-10-03Turkey flag
NUTRIFLEX LIPID SPECIAL INTRAVENOZ INFUZYONLUK EMULSIYON, 1875 MLPhosphate ion (22.5 mmol) + Acetate (67.5 mmol) + Alanine (8.73 g) + Arginine (4.86 g) + Aspartic acid (2.7 g) + Calcium (6 mmol) + Calcium chloride dihydrate (0.882 g) + Chlorine (67.5 mmol) + D-glucose (225 g) + Glutamic acid (6.32 g) + Glutamic acid (2.97 g) + Histidine (3.05 g) + Isoleucine (4.23 g) + Leucine (5.64 g) + Lysine (4.1 g) + Magnesium (6 mmol) + Magnesium acetate tetrahydrate (1.287 g) + Medium-chain triglycerides (37.5 g) + Methionine (3.53 g) + Phenylalanine (6.32 g) + Potassium (52.5 mmol) + Potassium acetate (5.151 g) + Proline (6.12 g) + Serine (5.4 g) + Sodium acetate trihydrate (0.416 g) + Sodium cation (75 mmol) + Sodium chloride (0.755 g) + Sodium hydroxide (1.464 g) + Sodium phosphate, monobasic, dihydrate (3.51 g) + Soybean oil (37.5 g) + Threonine (3.27 g) + Tryptophan (1.02 g) + Valine (4.68 g) + Zinc (0.045 mmol) + Zinc acetate dihydrate (9.87 mg)EmulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2007-07-032018-10-03Turkey flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
LiquidguardPhosphate ion (2.5 g/100mL)LiquidTopicalNano Care Deutschland AG2020-03-30Not applicableUS flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as non-metal phosphates. These are inorganic non-metallic compounds containing a phosphate as its largest oxoanion.
Kingdom
Inorganic compounds
Super Class
Homogeneous non-metal compounds
Class
Non-metal oxoanionic compounds
Sub Class
Non-metal phosphates
Direct Parent
Non-metal phosphates
Alternative Parents
Inorganic oxides
Substituents
Inorganic oxide / Non-metal phosphate
Molecular Framework
Not Available
External Descriptors
trivalent inorganic anion, phosphate ion (CHEBI:18367)
Affected organisms
Not Available

Chemical Identifiers

UNII
NK08V8K8HR
CAS number
14265-44-2
InChI Key
NBIIXXVUZAFLBC-UHFFFAOYSA-K
InChI
InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
IUPAC Name
phosphate
SMILES
[O-]P([O-])([O-])=O

References

General References
Not Available
Human Metabolome Database
HMDB0001429
ChemSpider
1032
BindingDB
50155537
RxNav
486961
ChEBI
18367
PDBe Ligand
PO4
Wikipedia
Phosphate
PDB Entries
117e / 13pk / 151l / 1914 / 1a2y / 1a40 / 1a6q / 1a7k / 1a9o / 1a9p
show 7323 more

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0SuspendedTreatmentHHRH / Hypercalcinuria / Hypophosphatemia / Rickets / X-Linked Hypophosphatemia1
Not AvailableCompletedOtherChronic Kidney Disease (CKD)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LiquidTopical2.5 g/100mL
Injection, emulsionIntravenous
EmulsionIntravenous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-1Chemaxon
pKa (Strongest Acidic)1.8Chemaxon
Physiological Charge-2Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area86.25 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity11.29 m3·mol-1Chemaxon
Polarizability4.93 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-105.4805532
predicted
DarkChem Lite v0.1.0
[M-H]-111.7231
predicted
DeepCCS 1.0 (2019)
[M-H]-105.4805532
predicted
DarkChem Lite v0.1.0
[M-H]-111.7231
predicted
DeepCCS 1.0 (2019)
[M+H]+113.752655
predicted
DeepCCS 1.0 (2019)
[M+H]+113.752655
predicted
DeepCCS 1.0 (2019)
[M+Na]+122.13096
predicted
DeepCCS 1.0 (2019)
[M+Na]+122.13096
predicted
DeepCCS 1.0 (2019)

Drug created at July 12, 2018 19:12 / Updated at June 12, 2020 16:53