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Displaying results 4451 - 4460 of 6951 in total
  1. Target

    Integrin alpha-5

    go.drugbank.com/bio_entities/BE0008988
    TargetHumans

    ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (PubMed:29030430). … ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling (PubMed:31331973).

    Synonyms: Fibronectin receptor subunit alpha
  2. Target

    Ephrin-B2

    go.drugbank.com/bio_entities/BE0010647
    TargetHumans

    Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. … The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.

    Synonyms: EPH-related receptor tyrosine kinase ligand 5Function: ephrin receptor binding
  3. Drug

    Rolapitant

    go.drugbank.com/drugs/DB09291
    ApprovedInvestigational

    Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) in adults. … Neurokinin-1 is also known as Tachykinin Receptor 1 (TACR1), Neurokinin 1 Receptor (NK1R), and Substance P Receptor (SPR).

    Categories: Neurokinin-1 Receptor Antagonists, Substance P/Neurokinin-1 Receptor Antagonist
  4. Drug

    Actinium

    go.drugbank.com/drugs/DB12860
    Investigational

    Actinium has been investigated for the treatment of Breast Cancer and Pulmonary Disease, Chronic Obstructive.

  5. Drug

    EXT608

    go.drugbank.com/drugs/DB18453
    Investigational

    EXT608 is a long-acting PTH derivative under investigation for the treatment of hyperparathyroidism.[L48270]

  6. Drug

    MUL001

    go.drugbank.com/drugs/DB18534
    Experimental

    MUL001 is live attenuated strain of _Salmonella typhimurium_ being investigated for the treatment of schwannomas.

  7. Drug

    Biopterin

    go.drugbank.com/drugs/DB03886
    Experimental

    A natural product that has been considered as a growth factor for some insects. [PubChem]

  8. Drug

    Elocalcitol

    go.drugbank.com/drugs/DB06194
    Experimental

    Elocalcitol is a calcitriol analog for inhibition of prostate cell growth; in phase II clinical trial in patients with benign prostate hyperplasia (4/2004).

  9. Drug

    Eladocagene exuparvovec

    go.drugbank.com/drugs/DB16780
    ApprovedInvestigational

    [A253697,L43672] Before the approval of this gene therapy, the treatment options for patients with AADC deficiency were limited to attempts to increase monoamine neurotransmitter production, decrease neurotransmitter

  10. Drug

    Danegaptide

    go.drugbank.com/drugs/DB11821
    Investigational

    Danegaptide has been investigated for the treatment of Focus of Study is STEMI.