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Displaying results 4451 - 4460 of 10000 in total
  1. Drug

    Pertuzumab

    go.drugbank.com/drugs/DB06366
    ApprovedInvestigational

    Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant therapy in the treatment of HER2-positive breast cancers at high risk of recurrence. … Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2).

    Mixtures: PHESGO® 1200 MG/600 MG, PHESGO® 1200 MG/600 MGCategories: Receptor, ErbB-2, antagonists & inhibitors, HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors
  2. Drug

    ZED-1227

    go.drugbank.com/drugs/DB19208
    Investigational

    ZED-1227 is under investigation in clinical trial NCT05305599 (Different Doses of ZED1227 vs. Placebo in NAFLD).

    Synonyms: Methyl (e,6s)-7-((1-(2-(2-ethylbutylamino)-2-oxo-ethyl)-2-oxo-3-pyridyl)amino)-6-((3-methylimidazole-4-carbonyl)amino)-7-oxo-hept-2-enoate, (2e,6s)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-1,2-dihydro-2-oxo-3-pyridinyl)amino)-6-(((1-methyl-1h-imidazol-5-yl)carbonyl)amino)-7-oxo-2-heptenoic acid methyl esterCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Iobitridol

    go.drugbank.com/drugs/DB12407
    ApprovedWithdrawn

    Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, IodinatedProducts: XENETİX 300 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 100 ML, Xenetix 250 (250 mg Jod/ml) - Parenterale Röntgenkontrastmittellösung
  4. Drug

    Levosulpiride

    go.drugbank.com/drugs/DB16021
    Investigational

    Synonyms: S-(-)-SulpirideMixtures: LEPRIT® ENZIMATICOGRAGEAS, LEPRIT® ENZIMATICOGRAGEAS
  5. Drug

    Malathion

    go.drugbank.com/drugs/DB00772
    Approved

    Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. … Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.

    Synonyms: O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl), O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethylInternational brands: Derbac-M
  6. Drug

    Vidarabine

    go.drugbank.com/drugs/DB00194
    ApprovedWithdrawn

    A nucleoside antibiotic isolated from Streptomyces antibioticus. … It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the

    Synonyms: 9-β-D-arabinofuranosyl-9H-purin-6-amine, 9-β-D-arabinofuranosyladenineInternational brands: Arasena-A
  7. Drug

    Mannitol

    go.drugbank.com/drugs/DB00742
    ApprovedInvestigational

    Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. … Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a

    Synonyms: D-Mannitol, D-(-)-MannitolInternational brands: Mannisol A
  8. Drug

    Gentamicin

    go.drugbank.com/drugs/DB00798
    ApprovedInvestigationalVet approved

    Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity

    International brands: G-Mycin, U-gencinMixtures: เดอมิกซ์-4, Amolg A
  9. Drug

    Disopyramide

    go.drugbank.com/drugs/DB00280
    ApprovedInvestigational

    A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar

    Categories: Antiarrhythmics, Class I, Cytochrome P-450 SubstratesProducts: Disopyramide Phosphate ER, NORPACE 100 MG KAPSÜL, 25 ADET
  10. Drug

    Pergolide

    go.drugbank.com/drugs/DB01186
    ApprovedVet approvedWithdrawn

    Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. … It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors.

    Categories: Heterocyclic Compounds with 4 or More Rings, Adrenergic alpha-1 Receptor AgonistsProducts: PERGOLID-NEURAX 1 MG, PERGOLIDE EG