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BBM-H901
go.drugbank.com/drugs/DB17704InvestigationalIt is being investigated for the treatment of hemophilia B.[A259048]
FB-101
go.drugbank.com/drugs/DB17956InvestigationalDeveloped by 1st Biotherapeutics, it is being investigated for the treatment of neurological disorders, such as Parkinson's Disease and amyotrophic lateral sclerosis (ALS).[L47102]
ARC183
go.drugbank.com/drugs/DB05124ExperimentalARC183 is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity … The key advantage of ARC183 compared to other thrombin inhibitors is its rapid onset of action and short half-life, giving it the potential to be an ideal agent for medical procedures that require rapid
Gantenerumab
go.drugbank.com/drugs/DB12034Investigationaltreatments include the related antibodies [aducanumab], which has been granted accelerated FDA approval, along with [bapineuzumab], [crenezumab], [donanemab], [lecanemab], and [solanezumab], which are at … Despite the clear association of Aβ aggregation with AD, treatments aimed at preventing Aβ aggregation or removing pre-existing Aβ plaques have shown little to no clinical benefit thus far and remain controversial
PlasmaCord
go.drugbank.com/drugs/DB16363Experimental[L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).
Zodasiran
go.drugbank.com/drugs/DB17626InvestigationalIt was granted an orphan drug designation for the treatment of homozygous familial hypercholesterolemia (HoFH).[L45869]
Cry5B
go.drugbank.com/drugs/DB17783ExperimentalWith demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal infections.[A259372, A259377]
BT200
go.drugbank.com/drugs/DB18333Investigational[A261491] It is under investigation for the treatment of von Willebrand disease and hemophilia A.[L48156]
AVR-RD-04
go.drugbank.com/drugs/DB18644ExperimentalIt consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.
BGT-DTDS
go.drugbank.com/drugs/DB18664ExperimentalIt is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS).