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Ammonium trichlorotellurate
go.drugbank.com/drugs/DB17740InvestigationalAmmonium trichlorotellurate is an investigational compound with anti-tumour [A259147] and anti-inflammatory properties.[A259152]
Synonyms: Ammonium trichloro [dioxoethylene-O,O') tellurium (IV), Ammonium trichloro(dioxyethylene-o,o')tellurium(iv)Categories: Compounds used in a research, industrial, or household settingButylphthalide
go.drugbank.com/drugs/DB12749InvestigationalButylphthalide has been used in trials studying the prevention of Restenosis.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingSynonyms: 3-n-butylphthalide, DL-3-n-butylphthalideUCB-1184197
go.drugbank.com/drugs/DB05092InvestigationalCDP323 is an antagonist of the _vascular cell adhesion molecule 1_ (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple … It is considered a small-molecule prodrug. CDP323 was originally developed by the British biopharmaceutical company Celltech plc.
Categories: Heterocyclic Compounds, 2-RingCR665
go.drugbank.com/drugs/DB05155ExperimentalIn preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that CR665 is a potent analgesic compound. … CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists.
GTS-21
go.drugbank.com/drugs/DB05708InvestigationalGTS-21 has been studied in multiple Phase I studies in healthy volunteers and one Phase I/II study in schizophrenic patients. In all studies, the compound was well tolerated. … In a Phase I multi-dose, double-blind, placebo controlled study in healthy adults, GTS-21 also demonstrated cognitive enhancement across all doses, with a statistically significant improvement in attention
Synonyms: DMXB-A, 3-(2,4-dimethoxybenzylidene) anabaseineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingFK352B
go.drugbank.com/drugs/DB06484ExperimentalFK352B is a adenosine A1 antagonist that is developed for the treatment of dialysis-induced hypotension.
Synonyms: 2-((2R)-1-((2E)-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)PROP-2-ENOYL)PIPERIDIN-2-YL)ACETIC ACID, 2-PIPERIDINEACETIC ACID, 1-((2E)-1-OXO-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)-2-PROPEN-1-YL)-, (2R)-Categories: Heterocyclic Compounds, 1-RingButhionine sulfoximine
go.drugbank.com/drugs/DB12870InvestigationalButhionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Categories: Compounds used in a research, industrial, or household settingSynonyms: Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, DL-buthionine-(S,R)-sulfoximineIrsogladine
go.drugbank.com/drugs/DB13056InvestigationalIrsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingDG041
go.drugbank.com/drugs/DB05027ExperimentalDG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and its complications. … DG041, an anti-platelet compound, has shown to be a selective and potent antagonist of the EP3 receptor for prostaglandins E2.
AME-527
go.drugbank.com/drugs/DB05879ExperimentalAME-527 is a humanized monoclonal antibody that recognizes human TNF-alpha (hTNF-alpha) with high affinity and specificity. … AME-527 was generated by protein engineering and identified from a library of antibody variants based on its improved binding properties.