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Displaying results 4461 - 4470 of 10000 in total
  1. Drug

    Chloral hydrate

    go.drugbank.com/drugs/DB01563
    ApprovedIllicitInvestigationalVet approved

    A hypnotic and sedative used in the treatment of insomnia. … The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments.

    Products: PMS-CHLORAL HYDRATE SYRUP 500 mg/5 ml, HIDRATO DE CLORAL 10%SOLUCION ORAL(GOTAS)
  2. Drug

    Idrevloride

    go.drugbank.com/drugs/DB18042
    Experimental

    Synonyms: D-glucitol, 1-deoxy-1-((2-(4-(4-(((((3,5-diamino-6-chloro-2-pyrazinyl)carbonyl)amino)iminomethyl)amino)butyl)phenoxy)ethyl)hexylamino)-, 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl((2S,3R,4R, 5R)-2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)-carbamimidoyl)pyrazine-2-carboxamide
  3. Drug

    Tolevamer

    go.drugbank.com/drugs/DB01344
    Approved

    It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: poly(styrene-4-sulfonic acid)
  4. Drug

    Mometasone

    go.drugbank.com/drugs/DB00764
    ApprovedInvestigational

    Mometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MOMECUTAN SALBE 1 MG/G, MOMETASONE EG
  5. Drug

    Eribulin

    go.drugbank.com/drugs/DB08871
    ApprovedInvestigational

    Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic … Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439].

    Categories: Heterocyclic Compounds, 1-RingProducts: ERIBULINA EG, HALAVEN 0.5 mg/ml solution for injection
  6. Drug

    Semaglutide

    go.drugbank.com/drugs/DB13928
    ApprovedInvestigational

    Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity. … [L41335] On May 31, 2023, the FDA issued a warning regarding the use of compounded semaglutide after receiving adverse event reports.

    Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsProducts: Wegovy® 1 mg/0.5 mL (1 mg/dose) Solution for injection in pre-filled pen, Ozempic® 1.34 mg/ml (1 mg/dose) Solution for injection in pre-filled pen
  7. Drug

    Avizakimab

    go.drugbank.com/drugs/DB18842
    Investigational

    Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).

    Synonyms: Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus musculus monoclonal bos161721 .gamma.1-chain), disulfide with human-mus musculus monoclonal bos161721
  8. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    It is currently marketed under the trademark TEMODAR® by Merck.[L32033] … [A229853, A229888, A229923, L32033] Following initial hydrolysis, further reactions liberate a highly reactive methyl diazonium cation capable of methylating various residues on adenosine and guanine bases

    Synonyms: 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one, 3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamideCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic Index
  9. Drug

    Cisplatin

    go.drugbank.com/drugs/DB00515
    ApprovedInvestigational

    Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung … It was the first member of its class, which now also includes carboplatin and oxaliplatin.

    Synonyms: (SP-4-2)-DIAMMINEDICHLOROPLATINUM, PLATINUM, DIAMMINEDICHLORO-, (SP-4-2)-Categories: Compounds used in a research, industrial, or household setting, OCT2 Substrates with a Narrow Therapeutic Index
  10. Drug

    Etigilimab

    go.drugbank.com/drugs/DB18854
    Investigational

    Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).

    Synonyms: Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32