Tolevamer is a potassium-binding resin used in the treatment of hyperkalemia. Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels.
- Mechanism
- Curator reviewed
Polystyrene sulfonate, which is not absorbed, binds excess potassium, carrying it out of the body. The indigestible potassium polystryene sulfonate complex is excreted with the faeces, preventing the absorption of potassium into the blood stream. Hence, the serum potassium level decreases.
- Primary indication
- Used to treat abnormally high potassium levels.Curator reviewed · 1 structured indication
- First approval
- Canada, 1997 · United States, 1958
- Also known as
- Polystyrene sulfonate · Polystyrene sulfonic acid · polystyrenesulfonic acid
- Brand names
Resolves to
Clinical / RWD
Targets
What you can answer from here — as of July 17, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Tolevamer, and which of those have an active Phase 3 trial?
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