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SR-123781A

SR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary syndromes (ACS).

Dutogliptin

Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.

Varespladib methyl

Studies showed that Varespladib methyl treatment resulted in significant positive changes on lipoproteins and inflammation.

BI 2536

BI 2536 is under investigation in clinical trial NCT00376623 (Efficacy and Safety of BI 2536 in Advanced or Metastatic Non Small Cell Lung Cancer).

GSK-923295

GSK-923295 is the first drug candidate to enter human clinical trials that specifically targets CENP-E and is currently in Phase I human clinical trials being conducted by GSK. … GSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown in nude mice, including models of colon, breast, ovarian, lung and other tumors.

Incadronic acid

Incadronate, or YM-175,[A202769] is a nitrogen containing bisphosphonate. … [A14426,A14431,A14427,A202769] Incadronic acid was first described in the literature in 1991.[A202289]

BI 4060107

BI 4060107 is a small molecule drug. … BI 4060107 is under investigation in clinical trial NCT07827144 (A Study to Test How Well Different Doses of BI 4060107 Are Tolerated by People With Advanced Cancer (Solid Tumours)).

Filanesib

Filanesib is a potent Kinesin Spindle Protein (KSP) inhibitor that caused marked tumor regression in preclinical models of human solid tumors and human leukemias, often leading to durable responses.

Peruvoside

Oxidized cellulose