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Displaying results 441 - 450 of 7654 in total
  1. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

    Synonyms: 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one, (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-oneProducts: PALONOSETRON DR. REDDY'S
  2. Drug

    Aripiprazole

    go.drugbank.com/drugs/DB01238
    ApprovedInvestigational

    [L45859,A4393] Aripiprazole was given FDA approval on November 15, 2002.[L6136] … [L45859] It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania.

    Categories: Dopamine D2 Receptor AntagonistsProducts: DM-AR, Nra-aripiprazole
  3. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    [A177550] Clinical findings have shown that children with ADHD have an abnormality in the dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene that may be at least … In contrast, low doses are found to selectively activate NE and DA neurotransmission within the prefrontal cortex which is an area of the brain thought to play a prominent role in ADHD pathophysiology,

    Products: RITALINA® LA 20 MG CAPSULAS DE LIBERACION PROLONGADA
  4. Drug

    Naldemedine

    go.drugbank.com/drugs/DB11691
    ApprovedInvestigational

    Naldemedine is an opioid receptor antagonist [FDA Label].

  5. Drug

    Dexamethasone

    go.drugbank.com/drugs/DB01234
    ApprovedInvestigationalVet approved

    [A188724] Dexamethasone was granted FDA approval on 30 October 1958.

    Mixtures: TQ OFTAMOX D UD®, TQ OFTAMOX® D UDProducts: Decadron DP, DEXAMETASONA FOSFATO DE SODIO
  6. Drug

    Fulvestrant

    go.drugbank.com/drugs/DB00947
    ApprovedInvestigational

    It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.

    Products: FULVESTRANT DR. REDDY'S
  7. Drug

    Acyclovir

    go.drugbank.com/drugs/DB00787
    ApprovedInvestigational

    [L7321] Acyclovir was granted FDA approval on 29 March 1982.[L7318]

    Mixtures: Activir Duo 50 mg/g + 10 mg/g CremeProducts: ACICLOVIR RATIO 200MG FTA, AVIREX-U
  8. Drug

    Chloramphenicol

    go.drugbank.com/drugs/DB00446
    ApprovedInvestigationalVet approvedWithdrawn

    (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this … An antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically.

    Synonyms: D-(−)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol, D-(−)-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenylethyl)acetamideProducts: PALMITATO DE CHLOROMYCETIN
  9. Drug

    Mertiatide

    go.drugbank.com/drugs/DB15780
    Investigational

    Products: NEPHROMAG EQUIPOS DE REACTIVOS PARA PREPARACION RADIOFARMACEUTICA.
  10. Drug

    Sunitinib

    go.drugbank.com/drugs/DB01268
    ApprovedInvestigational

    On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). … For these purposes, sunitinib is generally available as an orally administered formulation. Sunitinib inhibits cellular signaling by targeting multiple RTKs.

    Products: SUNITINIB DR. REDDY'S