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RGX-111
go.drugbank.com/drugs/DB17632InvestigationalDeveloped by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46666]
SM-1997
go.drugbank.com/drugs/DB18670Experimental[A261816] It is under investigation for the treatment of cutaneous sulfur mustard-induced injury.
Tulisokibart
go.drugbank.com/drugs/DB18719InvestigationalIt is being investigated for ulcerative colitis.
Metribolone
go.drugbank.com/drugs/DB02998ExperimentalIt binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
Elacridar
go.drugbank.com/drugs/DB04881InvestigationalElacridar (GW120918) is an oral bioenhancer that targets multiple drug resistance in tumors. In many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacri...
XmAb 2513
go.drugbank.com/drugs/DB06324InvestigationalIt has been investigated for the treatment of hodgkin’s lymphoma.
Poloxalene
go.drugbank.com/drugs/DB11451InvestigationalVet approvedIt belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen and two carbon atoms).
ONT-093
go.drugbank.com/drugs/DB14069ExperimentalIn pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics.
Ravagalimab
go.drugbank.com/drugs/DB16676InvestigationalRavagalimab is under investigation in clinical trial NCT03695185 (A Study to Investigate How Well Ravagalimab (ABBV-323) Works and How Safe It Is in Participants With Moderate to Severe Ulcerative Colitis