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Dronedarone
go.drugbank.com/drugs/DB04855ApprovedInvestigationalA safety concern for the risk of drug-induced hepatocellular injury has been issued following marketing of dronedarone.[L8800] … Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management.
Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexOditrasertib
go.drugbank.com/drugs/DB21526InvestigationalOditrasertib has a monoisotopic molecular weight of 295.11 Da. … Oditrasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Oditrasertib is a serine/threonine kinase inhibitor.
Ruserontinib
go.drugbank.com/drugs/DB21555InvestigationalRuserontinib has a monoisotopic molecular weight of 443.25 Da. … Ruserontinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Ruserontinib is a tyrosine kinase inhibitor.
Vociprotafib
go.drugbank.com/drugs/DB21559InvestigationalVociprotafib has a monoisotopic molecular weight of 450.16 Da. … Vociprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Vociprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor.
Enbezotinib
go.drugbank.com/drugs/DB21565InvestigationalEnbezotinib has a monoisotopic molecular weight of 424.17 Da. … Enbezotinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Enbezotinib is a tyrosine kinase inhibitor.
Polythiazide
go.drugbank.com/drugs/DB01324ApprovedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Vorinostat
go.drugbank.com/drugs/DB02546ApprovedInvestigationalVorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease … It is the first in a new class of agents known as histone deacetylase inhibitors.
BI 44370 TA
go.drugbank.com/drugs/DB16037InvestigationalBI 44370 TA is under investigation in clinical trial NCT00751803 (BI 44370 TA in Acute Migraine Attack).
Monlunabant
go.drugbank.com/drugs/DB21537InvestigationalMonlunabant has a monoisotopic molecular weight of 590.11 Da. … Monlunabant is a small molecule drug. The usage of the INN stem '-nabant' in the name indicates that Monlunabant is a cannabinoid receptor antagonist.