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Etynodiol
go.drugbank.com/drugs/DB13866ExperimentalEtynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. … While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see [DB00823]), not etynodiol.
Categories: Sex Hormones and Modulators of the Genital System, Cytochrome P-450 SubstratesSynonyms: (3β,17α)-19-Norpregn-4-en-20-yne-3,17-diol, 17α-Ethynyl-19-norandrost-4-ene-3β,17β-diolUCB-1184197
go.drugbank.com/drugs/DB05092InvestigationalCDP323 is an antagonist of the _vascular cell adhesion molecule 1_ (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple … It is considered a small-molecule prodrug. CDP323 was originally developed by the British biopharmaceutical company Celltech plc.
Categories: Heterocyclic Compounds, 2-RingVabicaserin
go.drugbank.com/drugs/DB12071InvestigationalVabicaserin has been used in trials studying the health services research and treatment of Schizophrenia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AgonistsUmifenovir
go.drugbank.com/drugs/DB13609Investigational[A191475,A191412] This dual activity may also confer additional protection against viral resistance, as the development of resistance to umifenovir does not appear to be significant. … Its invention is credited to a collaboration between Russian scientists from several research institutes 40-50 years ago, and reports of its chemical synthesis date back to 1993.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesAminocaproic acid
go.drugbank.com/drugs/DB00513ApprovedInvestigationalAn antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Mixtures: Relief and Nature Toothpast E Jasmine Mint, NAVI Black and C-ClinicSynonyms: 6-Aminocaproic acid, 6-aminohexanoic acidMexazolam
go.drugbank.com/drugs/DB15489Investigational[A184910] The use of benzodiazepines in the treatment of anxiety is generally a second line measure.[A184910] … Mexazolam (CS-386) is a benzodiazepine indicated for the treatment of anxiety with or without psychoneurotic conditions.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: SEDOXIL 1 MGFedratinib
go.drugbank.com/drugs/DB12500ApprovedInvestigationalFedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis. … [A183176,L8090] It is an anilinopyrimidine derivative.[A183188] Fedratinib was granted FDA approval on August 16, 2019.[L8090]
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsKW-7158
go.drugbank.com/drugs/DB05498ExperimentalThe therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root ganglion … KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity
Categories: Heterocyclic Compounds, 2-RingTebipenem pivoxil
go.drugbank.com/drugs/DB16840Approved[L57980] Tebipenem pivoxil is the first oral carbapenem approved in the United States, creating an outpatient option for patients who have limited or no alternative oral therapy. … Tebipenem pivoxil is an orally administered prodrug of tebipenem, a carbapenem antibacterial that kills bacteria by binding essential penicillin-binding proteins and disrupting cell wall biosynthesis.
Categories: MATE 1 Substrates, MATE 2 SubstratesNeisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen
go.drugbank.com/drugs/DB10799ApprovedInvestigationalThe vaccine contains *N. meningitis* serogroup c capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are extracted from Corynebacterium diphtheriae … Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria
Synonyms: Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen, Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine