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L523S
go.drugbank.com/drugs/DB06498InvestigationalAccording to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S)
Adafosbuvir
go.drugbank.com/drugs/DB14906InvestigationalAdafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).
(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide
go.drugbank.com/drugs/DB06941ExperimentalThis compound belongs to the phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group. This drug targets the protein S100B.
4-(4-fluoro-phenylazo)-5-imino-5H-pyrazol-3-ylamine
go.drugbank.com/drugs/DB08667ExperimentalThis compound belongs to the fluorobenzenes. These are compounds containing one or more fluorine atoms attached to a benzene ring. This substance targets the protein methionine aminopeptidase.
Cycloguanil
go.drugbank.com/drugs/DB14763ApprovedCycloguanil is the active metabolite of [proguanil].
RDEA806
go.drugbank.com/drugs/DB05228InvestigationalRDEA806 is a new HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with a high genetic barrier to resistance and a broad spectrum of activity.
Delapril
go.drugbank.com/drugs/DB13312InvestigationalCategories: Agents Acting on the Renin-Angiotensin SystemLNP-nCoVsaRNA Vaccine
go.drugbank.com/drugs/DB15799ExperimentalLNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV-2, which is used primarily by the virus to attach to and invade human cells. … As of July 2020, a clinical trial (COVAC1) is underway (ISRCTN17072692) to test the safety and immunogenicity of the vaccine.
Sparteine
go.drugbank.com/drugs/DB06727ApprovedWithdrawnSparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one of the products that have been withdrawn or removed from the market for reasons of safety or effectiveness … It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents.
AZD0947
go.drugbank.com/drugs/DB04848ExperimentalAs of March 2003, the drug was in phase II trials; however, as of October 2004, it no longer appeared on the company’s development pipeline. … AZD0947 is a K+ channel opener, which was under investigation by AstraZeneca for the treatment of overactive bladder.