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Perhexiline
go.drugbank.com/drugs/DB01074ApprovedPerhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingPovidone K30
go.drugbank.com/drugs/DB14478ApprovedA polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander. See [povidone] for full details.
Synonyms: 1-vinylpyrrolidin-2-one homopolymer, PVP K-30Products: Povidone K-30Cretostimogene grenadenorepvec
go.drugbank.com/drugs/DB05148InvestigationalCG0070 is investigated in clinical trials for treating bladder cancer. CG0070 is a solid. … It has been engineered to secrete GM-CSF, an immune stimulating hormone, which also serves as the adjuvant in cancer immunotherapy.
OXI-4503
go.drugbank.com/drugs/DB05143InvestigationalOXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. … Preclinical studies have demonstrated that OXI-4503 has (i) single-agent activity against a range of xenograft tumor models; and (ii) synergistic or additive effects when incorporated in various combination
Synonyms: Combretastatin A-1 bis(phosphate)Biochanin A
go.drugbank.com/drugs/DB15334ExperimentalBiochanin A is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: Biochanin AAlbinterferon Alfa-2B
go.drugbank.com/drugs/DB05396InvestigationalIn response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they ceased development of the drug. … The drug was under investigation as an alternative to pegylated IFN-α-2a for the treatment of hepatitis C.
Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: alb-IFNBiomed 101
go.drugbank.com/drugs/DB05851InvestigationalBiomed 101 is investigated for use/treatment in adverse effects (chemotherapy) and renal cell carcinoma. Biomed 101 is a solid. … Biomed 101 binds to the leukotriene B4 receptor, but does not affect interleukin-2 antitumor activity.
INCB7839
go.drugbank.com/drugs/DB05033InvestigationalIt represents a potentially important new class of targeted breast cancer therapy. It has shown promising clinical activity in heavily pretreated, refractory breast cancer patients. … INCB7839 is a novel, orally available ADAM metalloprotease inhibitor that is designed to block activation of the epidermal growth factor (EGFR) pathways.
Imazaquin
go.drugbank.com/drugs/DB04582ExperimentalSynonyms: (R)-imazaquinCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring2,5-di-tert-butylhydroquinone
go.drugbank.com/drugs/DB04638ExperimentalCategories: Compounds used in a research, industrial, or household setting