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Displaying results 4521 - 4530 of 9322 in total
  1. Drug

    Bexotegrast

    go.drugbank.com/drugs/DB16515
    Investigational

    The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in Series C financing to support further clinical … In addition, the compound is also currently in Phase 2a trials (NCT04565249) for the treatment of COVID-19 related acute respiratory distress syndrome[L31713].

  2. Drug

    Sinefungin

    go.drugbank.com/drugs/DB01910
    Experimental

    This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. … The proteins that adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and modification methylase RsrI.

  3. Drug

    Astaxanthin

    go.drugbank.com/drugs/DB06543
    Investigational

    It is found in the majority of aquatic organisms with red pigment. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. … It may be found in fish feed or some animal food as a color additive.

  4. Drug

    Roxarsone

    go.drugbank.com/drugs/DB11458
    ExperimentalVet approved

    The drug is also approved in the United States for use in pigs. … The addition of this compound to poultry feed improves weight gain and feed efficiency as well as prevent the growth of coccidian parasites.

  5. Drug

    Enzastaurin

    go.drugbank.com/drugs/DB06486
    Investigational

    Enzastaurin, an investigational, targeted, oral agent, will be evaluated at more than 100 sites worldwide for the treatment of relapsed glioblastoma multiforme (GBM), an aggressive and malignant form of

  6. Drug

    Hemin

    go.drugbank.com/drugs/DB03404
    ApprovedInvestigational

    Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.

  7. Drug

    XL999

    go.drugbank.com/drugs/DB05014
    Investigational

    XL999 has the potential to provide benefit to patients with lung cancer and acute myelogenous leukemia. … XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation and indirectly through inhibition of the host angiogenic response.

  8. Drug

    Famprofazone

    go.drugbank.com/drugs/DB16702
    Experimental

    [L34724] It is important to note that the drug is metabolized to [methamphetamine] and [amphetamine] in the body and can lead to positive tests results for illicit drug use. … [A236369,L34724] Famprofazone is included in the list of prohibited substances specified by the ‘World Anti-Doping Agency’ (WADA).[L34729]

  9. Drug

    Peginterferon alfacon-1

    go.drugbank.com/drugs/DB05860
    Experimental

    PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small … [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients with chronic hepatitis C infections.

  10. Drug

    alpha-Linolenic acid

    go.drugbank.com/drugs/DB00132
    ApprovedInvestigationalNutraceuticalWithdrawn

    It is a component of many common vegetable oils and is important to human nutrition.

    Mixtures: PRIM E CAPSULE, Huile D'onagre Vitamin E