PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small...
- Mechanism
- Curator reviewed
The effect of PEGylation is to increase drug circulation time in the bloodstream, improve drug solubility and stability, and reduce immunogenicity. The potential advantages of PEGylation are to decrease dosing frequency, improve drug efficacy and safety, improve stability, and simplify drug formulation.
- Primary indication
- Investigated for use/treatment in hepatitis (viral, C).Curator reviewed
- Also known as
- PEG INF alfacon-1 · PEG-Alfacon · PEG-Infergen · PEG-interferon alfacon-1 · Pegylated interferon alfacon-1
What you can answer from here — as of April 02, 2025
Which companies are running trials of Peginterferon alfacon-1, in which indications and phases, and which of those programs are still active?
Create a free account or log in to explore the full data card.
Create Account