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Risvodetinib
go.drugbank.com/drugs/DB21602InvestigationalRisvodetinib has a monoisotopic molecular weight of 574.28 Da.
SYNB1891
go.drugbank.com/drugs/DB17541InvestigationalSYNB1891 is a live, modified strain of the probiotic _Escherichia coli_ Nissle engineered to produce cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway.
Nifurizone
go.drugbank.com/drugs/DB19694ExperimentalNifurizone has a monoisotopic molecular weight of 307.09 Da.
Onametostat
go.drugbank.com/drugs/DB21480InvestigationalOnametostat has a monoisotopic molecular weight of 482.11 Da.
Mequitazine
go.drugbank.com/drugs/DB01071InvestigationalIt provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsNifurethazone
go.drugbank.com/drugs/DB20112ExperimentalNifurethazone has a monoisotopic molecular weight of 269.11 Da.
Gamcemetinib
go.drugbank.com/drugs/DB21624InvestigationalGamcemetinib has a monoisotopic molecular weight of 469.1 Da.
Brincidofovir
go.drugbank.com/drugs/DB12151ApprovedInvestigational[A235725,A235735] Due to its formulation as a pro-drug brincidofovir also carries a greater bioavailability than cidofovir,[A235740,A235725] allowing for oral administration rather than intravenous.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2B6 InhibitorsPirtobrutinib
go.drugbank.com/drugs/DB17472ApprovedInvestigationalIts high selectivity has been associated with lower discontinuation rates due to adverse events and a lower incidence of atrial fibrillation.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesReproxalap
go.drugbank.com/drugs/DB16688Investigational[L32990] NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome.[L32990]