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Alitretinoin
go.drugbank.com/drugs/DB00523ApprovedTretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. … It is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute).
Mixtures: Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05%Categories: Vitamin A, P-glycoprotein substratesMetyrapone
go.drugbank.com/drugs/DB01011ApprovedInvestigationalAn inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A Inducers19-norandrostenedione
go.drugbank.com/drugs/DB01434ExperimentalIllicitAfter 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency. … In the body 19-norandrostenedione is rapidly metabolized into [nandrolone], also known as nortestosterone.
Synonyms: delta,4-Estrene-3,17-dioneXanthan gum
go.drugbank.com/drugs/DB11253ApprovedThe major constituents include D-glucose, D-mannose, and D-glucuronic acid. Xanthan gum is a direct food additive permitted for direct addition to food for human consumption by the FDA. … It is used as a thickening agent and stabilizer in emulsions.
Mixtures: Medi SM 24K Gold Hydrogel Peptide Mask Pack, HydroGold 9Categories: Compounds used in a research, industrial, or household settingCCX915
go.drugbank.com/drugs/DB05159ExperimentalThe CCR2 receptor is thought to be of central importance to inflammatory diseases, such as multiple sclerosis (MS), Type II diabetes and atherosclerosis. … CCX915 is developed by ChemoCentryx which targets the chemokine receptor CCR2 and is in phase 1 of clinical trial for the treatment of Multiple Sclerosis and Neurologic Disorders.
Aluminum zirconium pentachlorohydrex gly
go.drugbank.com/drugs/DB11277ApprovedWithdrawnIt is a coordination complex of Aluminum Zirconium pentachlorohydrate and glycine. Its anhydrous form allows the molecule to absorb moisture. … Aluminum zirconium pentachlorohydrex gly, or Aluminum Zirconium Tetrachlorohydrex Glycine, is commonly used as an antiperspirant in many deodorant products.
Pipobroman
go.drugbank.com/drugs/DB00236ApprovedAn antineoplastic agent that acts by alkylation.
Synonyms: N,N-bis-(3-bromopropionyl)-piperazine, 1,4-bis(3-bromopropionyl)piperazineCategories: Heterocyclic Compounds, 1-RingMexazolam
go.drugbank.com/drugs/DB15489Investigational[A184910] The use of benzodiazepines in the treatment of anxiety is generally a second line measure.[A184910] … Mexazolam (CS-386) is a benzodiazepine indicated for the treatment of anxiety with or without psychoneurotic conditions.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: SEDOXIL 1 MGInsulin-like growth factor II
go.drugbank.com/drugs/DB14472InvestigationalIt is believed to be a major fetal growth factor in contrast to insulin-like growth factor I, which is a major growth factor in adults. … The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood.
Synonyms: SH-polypeptide-31, IGF-2Mometasone
go.drugbank.com/drugs/DB00764ApprovedInvestigationalMometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MOMECUTAN SALBE 1 MG/G, MONOVO 1MG/G EMU Z ANW HAU