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Displaying results 4571 - 4580 of 9333 in total
  1. Drug

    Diazepinomicin

    go.drugbank.com/drugs/DB12420
    Investigational

    It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well known chemotherapeutics, doxorubicin and mitomycin C. … Diazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme.

    Synonyms: 4,6,8-trihydroxy-10-(3,7,11-trimethyldodeca-2,6,10-trienyl)-5,10-dihydrodibenzo(b,e)(1,4)diazepin-11-one
  2. Drug

    Horse chestnut

    go.drugbank.com/drugs/DB13195
    Investigational

    The active component of this pure extract is escin, or aescin, that promotes blood circulation through the veins and reduces swelling and inflammation of the legs. … These seeds are processed to remove the toxic component, resulting in purified horse chestnut seed extract (HCSE) [A27200].

  3. Drug

    ACE393

    go.drugbank.com/drugs/DB05071
    Investigational

    ACE393 is an injectable vaccine designed to combat the bacterium Campylobacter jejuni, one of the greatest causes of bacterial diarrhoeal infections in the developed world.

  4. Drug

    QR-1123

    go.drugbank.com/drugs/DB17869
    Investigational

    QR-1123 is a first-in-class investigational RNA-based oligonucleotide designed to treat autosomal dominant retinitis pigmentosa due to the P23H mutation in the rhodopsin (_RHO_) gene.[L46782]

  5. Drug

    Isoxsuprine

    go.drugbank.com/drugs/DB08941
    ApprovedWithdrawn

    Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.

  6. Drug

    Formic acid

    go.drugbank.com/drugs/DB01942
    ApprovedInvestigational

    Formic acid (systematically called methanoic acid) is the simplest carboxylic acid. … It is an important intermediate in chemical synthesis and occurs naturally, most famously in the venom of bee and ant stings.

  7. Drug

    AD 337

    go.drugbank.com/drugs/DB05725
    Investigational

    The drug was created by Sosei pharmaceuticals to treat Fibromyalgia in female patients. … AD 337 was under investigation in clinical trial NCT00377039 (A Multicentre Trial to Determine the Efficacy and Safety of AD-337 in the Treatment of Fibromyalgia).

  8. Drug

    Florantyrone

    go.drugbank.com/drugs/DB08975
    ApprovedWithdrawn

    Florantyrone is used in the treatment of biliary dyskinesia

  9. Drug

    1,4-Dithiothreitol

    go.drugbank.com/drugs/DB04447
    Experimental

    A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. [PubChem]

  10. Drug

    G207

    go.drugbank.com/drugs/DB05827
    Investigational

    These viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores. … G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG.