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Displaying results 451 - 460 of 8415 in total
  1. Drug

    Fluconazole

    go.drugbank.com/drugs/DB00196
    ApprovedInvestigational

    It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose.[A174325] … It was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole].

    Products: PMS-fluconazole, PMS-fluconazole-150
  2. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623]

    Products: PMS-letrozole
  3. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    [L42880] It is a second-generation tetracycline that was first discovered in 1967.[A19429] Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines.

    Products: PMS-doxycycline
  4. Drug

    Duloxetine

    go.drugbank.com/drugs/DB00476
    ApprovedInvestigational

    [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder.

    Mixtures: DermacinRx DPN PakProducts: PMS-duloxetine
  5. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. … In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547].

    Products: PMS-ropinirole
  6. Drug

    Pioglitazone

    go.drugbank.com/drugs/DB01132
    ApprovedInvestigational

    Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus. … [L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence

    Products: PMS-pioglitazone
  7. Drug

    Safinamide

    go.drugbank.com/drugs/DB06654
    ApprovedInvestigational

    It was approved in Europe in February 2015, and in the United States on March 21, 2017.

  8. Drug

    Doxazosin

    go.drugbank.com/drugs/DB00590
    ApprovedInvestigational

    [A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285]

    Products: PMS-doxazosin
  9. Drug

    Dienogest

    go.drugbank.com/drugs/DB09123
    ApprovedInvestigational

    It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself. … In Europe, Australia, Malaysia, Singapore and Japan, dienogest single therapy is an approved treatment for endometriosis to alleviate painful symptoms of endometriosis and reduce endometriotic lesions

  10. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. … [A177946] This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.

    Products: PMS-mirtazapine