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Imatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigational[A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. … Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy".
Products: IMATINIB EG, IMATINIB DR. REDDY'SPinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalPinaverium bromide is the common ingredient in formulations, mostly as oral tablets. … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable
Mixtures: BROMUX D® 100/300 MG CÁPSULA.Products: BROMURO DE PINAVERIO 100 MG. TABLETAS, Bromuro de pinaverioEplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalThe resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone. … regulatory feedback of aldosterone on renin secretion.
Products: ACENOL 50 MG TABLETAS RECUBIERTAS, INSPRA® 25 MG TABLETAS RECUBIERTASCapecitabine
go.drugbank.com/drugs/DB01101ApprovedInvestigationalCapecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. … Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Synonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamateProducts: CAPEXEL TABLETAS 500 MG, NABTICEN® 500 MG TABLETASMethyldopa
go.drugbank.com/drugs/DB00968ApprovedInvestigational[A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. … [A232224] First introduced in 1960 as an antihypertensive agent, methyldopa was considered to be useful in certain patient populations, such as pregnant women and patients with renal insufficiency.
Products: ALDOMET 250 MG TABLETAS, METIL-DOPA TABLETAS 500Trametinib
go.drugbank.com/drugs/DB08911ApprovedInvestigational[A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission on June 30, 2014. … [A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma.
Products: MEKINIST®2 MG TABLETAS RECUBIERTAS, MEKINIST®0.5 MG TABLETAS RECUBIERTAS.Castor oil
go.drugbank.com/drugs/DB11113ApprovedNutraceuticalVet approvedIt can also be found in hard candies as a release agent and anti-sticking agent, or supplementary vitamins and mineral oral tablets as an ingredient for protective coatings. … Due to its renewability and high versatility in addition to being the only commercial source of a hydroxylated fatty acid [A31170], castor oil has been used as a vital raw material for the chemical industry
Products: Huile De Ricin, De La Cruz Castor OilTamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigational[Label] Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension. … [Label] Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor muscles in the bladder, allowing for better urinary flow.
Mixtures: DUTASTERIDE E TAMSULOSINA DOC, DUTASTERIDE E TAMSULOSINA DOCCategories: Drugs Used in Benign Prostatic HypertrophyPeppermint oil
go.drugbank.com/drugs/DB11198ApprovedInvestigationalThe use of peppermint oil in the management of irritable bowel syndrome (IBS) has been investigated in many clinical studies due to its relaxing effects on smooth muscle; however the evidence supporting … It is also an active ingredient in topical analgesics for the relief of joint and muscle pain. Peppermint oil can be applied topically to temporarily relieve tension-type headache.
Mixtures: Soda Mint Tab, Cellzyme ON-TOXProducts: Esprit De Menthe Poivref, Dr Tans Pain Releiving 3 day Herabl PatchGemfibrozil
go.drugbank.com/drugs/DB01241ApprovedInvestigational[L8525] Gemfibrozil was granted FDA approval on 21 December 1981.[L8525]
International brands: Gen-FibroProducts: Penta-gemfibrozil, STOLIP TABLETAS