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Zirconium panitumumab Zr-89
go.drugbank.com/drugs/DB19228InvestigationalZirconium panitumumab Zr-89 is under investigation in clinical trial NCT05423197 (Study Evaluating Zr-panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in Head and Neck Squamous
Sargramostim
go.drugbank.com/drugs/DB00020ApprovedInvestigationalIt is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Rusfertide
go.drugbank.com/drugs/DB17724ApprovedInvestigational[L64113] It is the first hepcidin mimetic approved for polycythemia vera.[L64113] … [L64098] It is a synthetic cyclic peptide that blocks the iron transporter ferroportin, reducing the availability of iron for red blood cell production and lowering hematocrit.
MGN-4893
go.drugbank.com/drugs/DB17338ExperimentalIn February 2011, it was granted FDA orphan designation for the treatment of polycythemia vera.[L47356]
Dipraglurant
go.drugbank.com/drugs/DB12733InvestigationalDipraglurant has been used in trials studying the treatment of Parkinson's Disease. It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).
Protionamide
go.drugbank.com/drugs/DB12667ApprovedInvestigationalWithdrawnProthionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Tribromsalan
go.drugbank.com/drugs/DB20138ApprovedWithdrawnTribromsalan has a monoisotopic molecular weight of 446.81 Da.
Tedisamil
go.drugbank.com/drugs/DB06200ExperimentalIt is currently being developed by Solvay and is currently under regulatory review by the United States Food and Drug Administration.
UC-781
go.drugbank.com/drugs/DB05871InvestigationalIt is a topical microbicide targeted against the AIDS virus.
Cyclandelate
go.drugbank.com/drugs/DB04838ApprovedWithdrawnIt may cause gastrointestinal distress and tachycardia. Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries.