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Imeglimin
go.drugbank.com/drugs/DB12509InvestigationalImeglimin has been used in trials studying the treatment of Type 2 Diabetes Mellitus.
Categories: Drugs Used in Diabetes, MATE 1 InhibitorsSmilagenin
go.drugbank.com/drugs/DB05450InvestigationalSmilagenin is a novel non-peptide, orally bioavailable neurotrophic factor inducer that readily reverses free radical neurotoxicity produced by 1-ethyl-4- phenylpyridium (MPP+) in dopaminergic neurones … P58 is a protein synthesis stimulant acts by restoring levels of proteins that are altered in the ageing brain, reversing the loss of nerve receptors in the ageing brain and potentially allowing for the
Inecalcitol
go.drugbank.com/drugs/DB04796InvestigationalSynonyms: (7E)-19-Nor-9,10-seco-14beta-cholesta-5,7-dien-23-yne-1alpha,3beta,25-triolCategories: Vitamin D and AnaloguesVarespladib methyl
go.drugbank.com/drugs/DB05737InvestigationalStudies showed that Varespladib methyl treatment resulted in significant positive changes on lipoproteins and inflammation.
Categories: Heterocyclic Compounds, 2-RingPhenobarbital
go.drugbank.com/drugs/DB01174ApprovedInvestigationalA barbituric acid derivative that acts as a nonselective central nervous system depressant. … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Mixtures: B-Donna, Re-PB HyosCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic IndexIMC-1C11
go.drugbank.com/drugs/DB06101ExperimentalIt is a chimeric anti-kinase insert domain-containing receptor (KDR) antibody that blocks VEGFR-KDR interaction and inhibits VEGFR-induced endothelial cell proliferation. … IMC-1C11 is an anti-angiogenesis agent.
Iodoxamic acid
go.drugbank.com/drugs/DB13539ExperimentalRadiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, IodinatedAluminium
go.drugbank.com/drugs/DB01370ApprovedInvestigationalWithdrawnA metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
MDX-214
go.drugbank.com/drugs/DB06110ExperimentalIt is developed for the treatment of EGF-R overexpressing cancers. … MDX-214 consists of recombinant human epidermal growth factor (EGF) genetically linked to a fully human antibody fragment that is designed to activate cytotoxic killing of cancer cells by immune effector